2-苯基-1-苯并呋喃合成路线 （共 220 条）
反应条件
1: bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; diisopropylamine / tetrahydrofuran / 0.67 h / 0 °C / |Inert atmosphere
2: tetrabutylammomium bromide; dihydrogen peroxide; sodium hydroxide / dichloromethane; water / 0 °C
3: silver trifluoromethanesulfonate; methanol; {1,3-bis[2,6-di(propan-2-yl)phenyl]-1,3-dihydro-2H-imidazol-2-ylidene}AuCl; toluene-4-sulfonic acid / dichloromethane-d2 / 0.17 h / 20 °C
View Scheme
参考文献
Wang, Tao; Shi, Shuai; Vilhelmsen, Mie Hojer; Zhang, Tuo; Rudolph, Matthias; Rominger, Frank; Hashmi, A. Stephen K.
Chemistry - A European Journal, 2013 , vol. 19, # 37 p. 12512 - 12516
反应条件
1: bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; diisopropylamine / tetrahydrofuran / 0.67 h / 0 °C / |Inert atmosphere
2: tetrabutylammomium bromide; dihydrogen peroxide; sodium hydroxide / dichloromethane; water / 0 °C
3: silver trifluoromethanesulfonate; methanol; {1,3-bis[2,6-di(propan-2-yl)phenyl]-1,3-dihydro-2H-imidazol-2-ylidene}AuCl; toluene-4-sulfonic acid / dichloromethane-d2 / 0.17 h / 20 °C
View Scheme
参考文献
Wang, Tao; Shi, Shuai; Vilhelmsen, Mie Hojer; Zhang, Tuo; Rudolph, Matthias; Rominger, Frank; Hashmi, A. Stephen K.
Chemistry - A European Journal, 2013 , vol. 19, # 37 p. 12512 - 12516
反应条件
n-butyllithium; hydrogen iodide; diisopropylamine
1)THF, -60 deg C, 20 min; 2)HOAc, reflux 4h; Yield given. Multistep reaction;
参考文献
Koenigkramer, Rusty E.; Zimmer, Hans
Journal of Organic Chemistry, 1980 , vol. 45, # 20 p. 3994 - 3998
反应条件
in methanol
T=0 - 20°C; Cyclization; alkynylation; 12 h;
参考文献
Kitamura, Tsugio; Zheng, Lei; Fukuoka, Takahiro; Fujiwara, Yuzo; Taniguchi, Hiroshi; Sakurai, Makoto; Tanaka, Ryuichi
Journal of the Chemical Society. Perkin Transactions 2, 1997 , # 8 p. 1511 - 1515
反应条件
Condensation; UV-irradiation;
参考文献
Rajes, Cheruvallil S.; Givens, Richard S.; Wirz, Jakob
Journal of the American Chemical Society, 2000 , vol. 122, # 4 p. 611 - 618
反应条件
1: 74 percent / 1.) sec-BuLi / 1.) -105 deg C
2: 60 percent / formic acid / 1 h / Heating
View Scheme
参考文献
Date, Matsuhiro; Kawanishi, Kenji; Hori, Takako; Watanabe, Mitsuaki; Furukawa, Sunao
Chemical & Pharmaceutical Bulletin, 1989 , vol. 37, # 10 p. 2884 - 2886
反应条件
β-cyclodextrin
6 h; Irradiationalso in the presence of γ-cyclodextrin; Yield given;
参考文献
Bantu; Kotch; Lees
Tetrahedron Letters, 1993 , vol. 34, # 13 p. 2039 - 2042
反应条件
1: 74 percent / 1.) sec-BuLi / 1.) -105 deg C
2: 60 percent / formic acid / 1 h / Heating
View Scheme
参考文献
Date, Matsuhiro; Kawanishi, Kenji; Hori, Takako; Watanabe, Mitsuaki; Furukawa, Sunao
Chemical & Pharmaceutical Bulletin, 1989 , vol. 37, # 10 p. 2884 - 2886
反应条件
1: diethyl ether
2: NaHSO3; water / und Zersetzen der entstandenen Disulfit-Verbindung mit verd.Schwefelsaeure
3: glacial acetic acid; hydrobromic acid / 150 °C
View Scheme
参考文献
Stoermer; Frick
Chemische Berichte, 1924 , vol. 57, p. 27
参考文献
Dilthey; Quint
Journal fuer Praktische Chemie (Leipzig), 1931 , vol. <2> 131, p. 1,26
