2-苯基-1-苯并呋喃合成路线 （共 220 条）
反应条件
copper(l) iodide; 1,10-phenanthroline; caesium carbonate in N,N-dimethyl-formamide
T=130°C; 24 h; Inert atmosphere;
参考文献
Zhao, Dongbing; Gao, Chao; Su, Xiaoyu; He, Yunqing; You, Jingsong; Xue, Ying
Chemical Communications, 2010 , vol. 46, # 47 p. 9049 - 9051
反应条件
1: iodobenzene; 2-methyl-but-3-yn-2-ol With copper(l) iodide; diisopropylamine; bis-triphenylphosphine-palladium(II) chloride
T=80°C; Sonogashira coupling;
2: O-triisopropylsilyl-2-iodophenol With potassium hydroxide; copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride
T=80°C; Sonogashira coupling;
3: With tetrabutyl ammonium fluoride in tetrahydrofuran
T=80°C; Further stages.;
参考文献
Csekei, Marton; Novak, Zoltan; Kotschy, Andras
Tetrahedron, 2008 , vol. 64, # 37 p. 8992 - 8996
反应条件
dicyclohexyl(2′,6′-dimethoxybiphenyl-2-yl)phosphine; potassium phosphate; palladium diacetate in tetrahydrofuran; water
T=60°C; Suzuki coupling; 4.5 h; Inert atmosphere;
参考文献
Chan, Julian M.W.; Amarante, Giovanni W.; Toste, F. Dean
Tetrahedron, 2011 , vol. 67, # 24 p. 4306 - 4312
参考文献
Davies; Middleton
Journal of the Chemical Society, 1958 , p. 822,824
Full Text Show Details
Davies; Middleton
Journal of the Chemical Society, 1959 , p. 3544,3545
反应条件
triethylamine hydroiodide; copper dichloride; palladium dichloride in 1,2-dichloro-ethane
T=20°C; 8 h;
参考文献
Liang, Yun; Tang, Shi; Zhang, Xu-Dong; Mao, Li-Qiu; Xie, Ye-Xiang; Li, Jin-Heng
Organic Letters, 2006 , vol. 8, # 14 p. 3017 - 3020
反应条件
1: 3,4,5-trimethoxyphenylboronic acid With tris-(dibenzylideneacetone)dipalladium(0); caesium carbonate; cesium fluoride; bis[2-(diphenylphosphino)phenyl] ether
Inert atmosphere;
2: α,β-dichlorovinyl phenyl ether in tetrahydrofuran
Inert atmosphereReflux;
参考文献
Geary, Laina M.; Hultin, Philip G.
European Journal of Organic Chemistry, 2010 , # 29 p. 5563 - 5573
反应条件
1: With n-butyllithium in tetrahydrofuran; hexane
T=-78°C; Inert atmosphere;
2: With water; ammonium chloride in tetrahydrofuran; hexane
Inert atmosphere;
参考文献
Shi, Wei; Coleman, Robert S.; Lowary, Todd L.
Organic and Biomolecular Chemistry, 2009 , vol. 7, # 18 p. 3709 - 3722
反应条件
1: in tetrahydrofuran; toluene
T=20 - 55°C; 1.5 h; Inert atmosphere;
2: With hydrogenchloride in tetrahydrofuran; toluene
参考文献
Pei, Tao; Chen, Cheng-Yi; Dimichele, Lisa; Davies, Ian W.
Organic Letters, 2010 , vol. 12, # 21 p. 4972 - 4975
反应条件
1: With palladium diacetate; xantphos in N-dodecane; butan-1-ol
T=25°C; Suzuki-Miyaura Coupling; 0.0833333 h; Inert atmosphereGlovebox;
2: With cesium hydroxide monohydrate in N-dodecane; water; butan-1-ol
T=25°C; Suzuki-Miyaura Coupling; Inert atmosphereGlovebox;
参考文献
Yang, Junfeng; Liu, Sijia; Zheng, Jian-Feng; Zhou, Jianrong
European Journal of Organic Chemistry, 2012 , # 31 p. 6248 - 6259,12
Title/Abstract Full Text Show Details
Yang, Junfeng; Liu, Sijia; Zheng, Jian-Feng; Zhou, Jianrong
European Journal of Organic Chemistry, 2012 , # 31 p. 6248 - 6259
反应条件
1: With palladium diacetate; xantphos in N-dodecane; butan-1-ol
T=80°C; Suzuki-Miyaura Coupling; 1 h; Inert atmosphereGlovebox;
2: With cesium hydroxide monohydrate in N-dodecane; water; butan-1-ol
T=25°C; Suzuki-Miyaura Coupling; Inert atmosphereGlovebox;
参考文献
Yang, Junfeng; Liu, Sijia; Zheng, Jian-Feng; Zhou, Jianrong
European Journal of Organic Chemistry, 2012 , # 31 p. 6248 - 6259,12
Title/Abstract Full Text Show Details
Yang, Junfeng; Liu, Sijia; Zheng, Jian-Feng; Zhou, Jianrong
European Journal of Organic Chemistry, 2012 , # 31 p. 6248 - 6259
