4,4'-二溴-2,2'-联吡啶合成路线 （共 17 条）
反应条件
N,N,N',N,-tetramethylethylenediamine; 1,5-bis-(diphenylphosphino)-pentane; palladium diacetate in 1,3,5-trimethyl-benzene 12 h; Inert atmosphereReflux;
参考文献
Duong, Adam; Maris, Thierry; Lebel, Olivier; Wuest, James D.
Journal of Organic Chemistry, 2011 , vol. 76, # 5 p. 1333 - 1341
反应条件
1: With sodium carbonate in water; toluene 0.25 h; Inert atmosphere; 2: With tetrakis(triphenylphosphine) palladium(0) in water; toluene Suzuki coupling; 14 h; Reflux;
参考文献
Han, Won-Sik; Han, Jung-Kyu; Kim, Hyun-Young; Choi, Mi Jin; Kang, Yong-Soo; Pac, Chyongjin; Kang, Sang Ook
Inorganic Chemistry, 2011 , vol. 50, # 8 p. 3271 - 3280
反应条件
water in tetrahydrofuran -90°C; then hydrolysis;
参考文献
Nakashima, Kazuaki; Shinkai, Seiji
Chemistry Letters, 1994 , # 7 p. 1267 - 1270
反应条件
tetrakis(triphenylphosphine) palladium(0); triethylamine; triphenylphosphine in toluene T=110°C; 6 h;
参考文献
Penicaud, Virginie; Odobel, Fabrice; Bujoli, Bruno
Tetrahedron Letters, 1998 , vol. 39, # 22 p. 3689 - 3692
反应条件
tetrakis(triphenylphosphine) palladium(0); boronic acid; sodium carbonate in methanol; water; toluene
T=100°C;
参考文献
Damrauer, Niels H.; Boussie, Thomas R.; Devenney, Martin; McCusker, James K.
Journal of the American Chemical Society, 1997 , vol. 119, # 35 p. 8253 - 8268
反应条件
tributyl-amine; bis-triphenylphosphine-palladium(II) chloride
Carboxylation; esterification; P=760.051 Torr; Heating;
参考文献
El-Ghayoury; Ziessel
Journal of Organic Chemistry, 2000 , vol. 65, # 23 p. 7757 - 7763
反应条件
1: With tetrakis(triphenylphosphine) palladium(0); potassium carbonate in N,N-dimethyl-formamide
T=85 - 95°C; Suzuki reaction; 24 h;
2: in N,N-dimethyl-formamide
T=115°C; 5 h; Further stages.;
参考文献
Carlson, Brenden; Phelan, Gregory D.; Kaminsky, Werner; Dalton, Larry; Jiang, Xuezhong; Liu, Sen; Jen, Alex K.-Y.
Journal of the American Chemical Society, 2002 , vol. 124, # 47 p. 14162 - 14172
