R-1,1'-联-2-萘酚合成路线 （共 56 条）
反应条件
1: in methanol T=50°C; 1 h; 2: With hydrogenchloride in water; ethyl acetate Product distribution / selectivity;
参考文献
WO2011/86566 A1, ;
Page/Page column 32-33 ;
反应条件
lithium aluminium tetrahydride
参考文献
Wang, Min; Liu, Shang Zhong; Liu, Jun; Hu, Bing Fang
Journal of Organic Chemistry, 1995 , vol. 60, # 22 p. 7364 - 7365
反应条件
in benzene T=80.9°C; var. temp. and solvents; activation energy and frequency factor; also as salts with (R,R)-1,2-cyclohexanediamine and (R,R)-1,2-diphenyl-1,2-ethanediamine; Rate constantThermodynamic data;
参考文献
Bulletin of the Chemical Society of Japan, , vol. 66, # 7 p. 2002 - 2005
参考文献
Chemistry Letters, , p. 2085 - 2088
反应条件
L-proline; copper dichloride T=60°C; 0.5 h; Neat (no solvent); optical yield given as percent eeenantioselective reaction;
参考文献
Tavana, Mahdie; Montazeri, Nasser; Imanzadeh, Gholamhassan
Asian Journal of Chemistry, 2011 , vol. 23, # 7 p. 3097 - 3100
反应条件
1: 127 mg / LiAlH4 / diethyl ether / 4 h / Heating 2: benzene; pyridine / room temp., overnight, reflux, 3 h 3: 42 percent / copper powder / dimethylformamide 4: 73 percent / KOH / aq. ethanol View Scheme
参考文献
Bulletin of the Chemical Society of Japan, , vol. 57, # 7 p. 1943 - 1947
反应条件
1: Boc-[(R)-Binol-22-C-6]-(R)-Bip-OMe With boron tribromide in dichloromethane T=20°C; 40 h; 2: methanol With thionyl chloride T=20°C; 96 h; Further stages.;
参考文献
Tetrahedron, , vol. 64, # 10 p. 2307 - 2320
反应条件
2: 92 percent / 0.1 N KOH / ethanol / 18 h / 25 °C View Scheme
参考文献
Tetrahedron Letters, , vol. 34, # 38 p. 6057 - 6058
反应条件
1: methanol; diethyl ether 2: KOH / methanol 3: (i) SOCl2, (ii) aq. NaN3, acetone, (iii) aq. KOH 4: (i) aq. HCl, NaNO2, (ii) H3PO2 5: (i) BBr3, CH2Cl2, (ii) H2O View Scheme
参考文献
Tetrahedron, , vol. 27, p. 5999 - 6009
反应条件
boron tribromide in dichloromethane T=0 - 20°C; 20 h; Inert atmosphere;
参考文献
Journal of Organic Chemistry, , vol. 78, # 14 p. 7086 - 7092
