1,1-二甲基-1H-茚合成路线 （共 15 条）
反应条件
platinum (II) chloride; copper(I) bromide in toluene
T=120°C; regioselective reaction;
参考文献
Yang, Shangdong; Li, Zigang; Jian, Xing; He, Chuan
Angewandte Chemie, International Edition, 2009 , vol. 48, p. 3999 - 4001
Angewandte Chemie, 2009 , vol. 121, p. 4059 - 4061
反应条件
toluene-4-sulfonic acid
T=80 - 100°C;
参考文献
Eisch, John J.; Fichter, Kenneth C.
Journal of Organometallic Chemistry, 1983 , vol. 250, # 1 p. 63 - 82
反应条件
1: 97 percent / LiAlH4 / diethyl ether / Heating
2: 84 percent / p-toluenesulfonic acid / 80 - 100 °C
View Scheme
参考文献
Eisch, John J.; Fichter, Kenneth C.
Journal of Organometallic Chemistry, 1983 , vol. 250, # 1 p. 63 - 82
反应条件
magnesium; lithium chloride; copper dichloride
1.) THF, 2.) THF, RT, overnight; Multistep reaction. Title compound not separated from byproducts;
参考文献
Buckle; Arch; Edge; Foster; Houge-Frydrych; Pinto; Smith; Taylor; Tedder; Webster
Journal of Medicinal Chemistry, 1991 , vol. 34, # 3 p. 919 - 926
反应条件
n-butyllithium
1.) diethyl ether, n-hexane, room temp., 0.5 h, 2.) room temp., 5 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Morrison, Harry; Giacherio, David; Palensky, Frederick J.
Journal of Organic Chemistry, 1982 , vol. 47, # 6 p. 1051 - 1058
反应条件
EPZ-10 in nitromethane
Heating; Yields of byproduct given;
参考文献
Schaik, Henk-Peter van; Vijn, Robert-Jan; Bickelhaupt, Friedrich
Angewandte Chemie, 1994 , vol. 106, # 15/16 p. 1703 - 1704
反应条件
1: (i) PCl5, (ii) AlCl3
2: NaBH4
3: aq. H2SO4 / Heating
View Scheme
参考文献
Bingham,A.J. et al.
Journal of the Chemical Society [Section] C: Organic, 1970 , p. 1879 - 1883
反应条件
1: (i) nBuLi, (ii) /BRN= 969135/
2: (i) nBuLi, (ii) /BRN= 969135/
View Scheme
参考文献
Meurling,L.
Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1974 , vol. 28, p. 295 - 300
反应条件
(i) nBuLi, (ii) /BRN= 969135/; Multistep reaction;
参考文献
Meurling,L.
Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1974 , vol. 28, p. 295 - 300
反应条件
T=42°C; 0.0166667 h; Irradiation;
参考文献
Suarez, Marie L.; Duguid, Robert J.; Morrison, Harry
Journal of the American Chemical Society, 1989 , vol. 111, # 16 p. 6384 - 6391
