(2R,3S)-2,3-二羟基-4-异丙氧基-gamma-丁内酯环己基缩酮合成路线 （共 5 条）
反应条件
pyridinium p-toluenesulfonate 1.5 h; Heating;
参考文献
Borcherding; Scholtz; Borchardt
Journal of Organic Chemistry, 1987 , vol. 52, # 24 p. 5457 - 5461
反应条件
1: 1.) aq. KOH, 2.) aq. KIO4 / 1.) 40 deg C, 15 min, 2.) 4 deg C, 5 h 2: pyridinium p-toluenesulfonate / 12 h / 60 °C View Scheme
参考文献
Marien; Esmans; Lemiere; Dommisse
Synthetic Communications, 1997 , vol. 27, # 2 p. 205 - 224
反应条件
1: 60 percent / FeCl3, Drierite / 3 h / 50 °C 2: 1.) aq. KOH, 2.) aq. KIO4 / 1.) 40 deg C, 15 min, 2.) 4 deg C, 5 h 3: pyridinium p-toluenesulfonate / 12 h / 60 °C View Scheme
参考文献
Marien; Esmans; Lemiere; Dommisse
Synthetic Communications, 1997 , vol. 27, # 2 p. 205 - 224
反应条件
pyridinium p-toluenesulfonate T=60°C; 2.5 h; influence of temperature, reaction time; Product distribution;
参考文献
Marien; Esmans; Lemiere; Dommisse
Synthetic Communications, 1997 , vol. 27, # 2 p. 205 - 224
反应条件
n-butyllithium
1.) THF, hexane, - 78 deg C, 15 min, 2.) THF, hexane, - 78 deg, 2.5 h; Yield given. Multistep reaction;
参考文献
Marien; Esmans; Lemiere; Dommisse
Synthetic Communications, 1997 , vol. 27, # 2 p. 205 - 224
