双(3,5-二甲基苯基)氧化膦合成路线 （共 8 条）
反应条件
1: With magnesium in tetrahydrofuran T=40 - 50°C; Inert atmosphere; 2: With phosphorous acid diethyl ester in tetrahydrofuran T=0°C; 1.5 h; Inert atmosphere;
参考文献
Chemistry Letters, , vol. 42, # 9 p. 1035 - 1037
反应条件
1: With iodine; magnesium; ethylene dibromide in tetrahydrofuran T=20°C; 1.5 h; 2: 1-bromo-3,5-dimethyl-benzene in tetrahydrofuran T=25 - 40°C; 0.666667 h; 3: phosphorous acid diethyl ester in tetrahydrofuran T=-33 - 0°C; 0.5 h;
参考文献
EP1452537 A1, ;
Page 25 ;
反应条件
nitrogen; iodine; potassium carbonate; magnesium in tetrahydrofuran; chloroform; water
反应条件
monobutyl butyl phosphonate; potassium hydride in diethyl ether 4 h;
参考文献
Journal of the American Chemical Society, , vol. 116, # 22 p. 9869 - 9882
反应条件
1: 1-bromo-3,5-dimethyl-benzene With iodine; magnesium in tetrahydrofuran Inert atmosphere; 2: phosphonic acid diethyl ester in tetrahydrofuran T=0°C; 2.25 h; Inert atmosphere;
参考文献
Angewandte Chemie - International Edition, , vol. 52, # 17 p. 4549 - 4553
Angew. Chem., , vol. 125, # 17 p. 4647 - 4651,5
反应条件
cupric triflate; 1,1,3,3-tetramethyldisiloxane in toluene T=100°C; Inert atmosphere;
参考文献
Li, Yuehui; Das, Shoubhik; Zhou, Shaolin; Junge, Kathrin; Beller, Matthias
Journal of the American Chemical Society, 2012 , vol. 134, # 23 p. 9727 - 9732
反应条件
dimethylsulfide borane complex; water in tetrahydrofuran T=20°C; 1.5 h;
参考文献
Synlett, , # 7 p. 1012 - 1016
反应条件
phosphorus trichoride in dichloromethane 1.5 h;
参考文献
Casalnuovo, Albert L.; RajanBabu, T. V.; Ayers, Timothy A.; Warren, Timothy H.
Journal of the American Chemical Society, 1994 , vol. 116, # 22 p. 9869 - 9882
