对氯苯乙酸合成路线

参考文献

GLAXO GROUP LIMITED
Patent: WO2007/122156 A1, 2007 ;
Location in patent: Page/Page column 90 ;
WO 2007/122156 A1

1878-66-6对氯苯乙酸

33155-59-82-(4-氯苯基)乙酸叔丁酯

参考文献

GLAXO GROUP LIMITED
Patent: WO2009/47336 A1, 2009 ;
Location in patent: Page/Page column 57 ;
WO 2009/047336 A1

1878-66-6对氯苯乙酸+

71432-55-82-叔丁基-1,3-二异丙基异脲

33155-59-82-(4-氯苯基)乙酸叔丁酯

参考文献

MERCK SHARP andamp; DOHME CORP.; LIN, Songnian; STEVENSON, Christian, P.; PARMEE, Emma, R.; XU, Libo; LIAO, Xibin; METZGER, Edward; LIANG, Rui; ZHANG, Fengqi; STELMACH, John, E.
Patent: WO2010/30722 A1, 2010 ;
Location in patent: Page/Page column 80 ;
WO 2010/030722 A1

1878-66-6对氯苯乙酸+

36805-97-7N,N-二甲基甲酰胺二叔丁基缩醛

33155-59-82-(4-氯苯基)乙酸叔丁酯

参考文献

Allen, Darin A.; Pham, Phuongly; Choong, Ingrid C.; Fahr, Bruce; Burdett, Matthew T.; Lew, Willard; DeLano, Warren L.; Gordon, Eric M.; Lam, Joni W.; O'Brien, Tom; Lee, Dennis
Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 21 p. 3651 - 3655

1878-66-6对氯苯乙酸

35730-03-1

参考文献

Turro, Nicholas J.; Weed, Gregory C.
Journal of the American Chemical Society, 1983 , vol. 105, # 7 p. 1861 - 1868

1878-66-6对氯苯乙酸

34402-92-1

参考文献

Bolli, Martin H.; Boss, Christoph; Binkert, Christoph; Buchmann, Stephan; Bur, Daniel; Hess, Patrick; Iglarz, Marc; Meyer, Solange; Rein, Josiane; Rey, Markus; Treiber, Alexander; Clozel, Martine; Fischli, Walter; Weller, Thomas
Journal of Medicinal Chemistry, 2012 , vol. 55, # 17 p. 7849 - 7861

1878-66-6对氯苯乙酸

3327-51-31-氯-4-甲基苯

参考文献

Gilbert, Bruce C.; Scarratt, Cathryn J.; Thomas, C. Barry; Young, John
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1987 , p. 371 - 380

1878-66-6对氯苯乙酸+

64-17-5乙醇

14062-24-9对氯苯乙酸乙酯

参考文献

ARRAY BIOPHARMA INC.
Patent: WO2005/51304 A2, 2005 ;
Location in patent: Page/Page column 105 ;
WO 2005/051304 A2

1878-66-6对氯苯乙酸

14062-24-9对氯苯乙酸乙酯

参考文献

Hoffman-La Roche Inc.
Patent: US6610846 B1, 2003 ;
US 6610846 B1

1878-66-6对氯苯乙酸+

60-29-7乙醚

14062-24-9对氯苯乙酸乙酯

参考文献

Prana Biotechnology Limited
Patent: WO2004/31161 A1, 2004 ;
Location in patent: Page 133 ;