188290-36-0合成路线 （共 917 条）
反应条件
n-butyllithium; 4-toluenesulfonyl azide
1.) Et2O, hexane, reflux, 1 h, 2.) Et2O, hexane, from -70 deg C to 0 deg C, 5 h; Yield given. Multistep reaction;
参考文献
Spinelli, Domenico; Zanirato, Paolo
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1993 , # 6 p. 1129 - 1133
反应条件
cerium(IV) sulphate in methanol; water
4 h; Ambient temperature;
参考文献
Weinstock, Leonard M.; Corley, Edward; Abramson, Newton L.; King, Anthony O.; Karady, Sandor
Heterocycles, 1988 , vol. 27, # 11 p. 2627 - 2634
参考文献
Jenks, William S.; Heying, Melanie J.; Stoffregen, Stacey A.; Rockafellow, Erin M.
Journal of Organic Chemistry, 2009 , vol. 74, # 7 p. 2765 - 2770
反应条件
aluminium trichloride in benzene
0.5 h; Heating;
参考文献
Von Kieseritzky, Fredrik; Hellberg, Jonas; Wang, Xiangjun; Inganaes, Olle
Synthesis, 2002 , # 9 p. 1195 - 1200
反应条件
aluminium trichloride
参考文献
Leuckart; Schmidt,M.
Chemische Berichte, 1885 , vol. 18, p. 2340
Journal fuer Praktische Chemie (Leipzig), 1890 , vol. <2> 41, p. 320
反应条件
1: thiophene With n-butyllithium in tetrahydrofuran; hexane
T=0 - 20°C; 3.25 h;
2: zinc(II) chloride in tetrahydrofuran; hexane
T=0 - 20°C; 1 h;
参考文献
Koldobskii; Tsvetkov; Shilova; Solodova; Kalinin
Russian Chemical Bulletin, 2009 , vol. 58, # 11 p. 2271 - 2275
Izv. Akad. Nauk, Ser. Khim., 2009 , # 11 p. 2202 - 2206,5
反应条件
1: With tert.-butyl lithium in tetrahydrofuran; cyclohexane
T=-78 - -30°C; 0.5 h;
2: With zinc(II) chloride in tetrahydrofuran; cyclohexane
T=-78 - 20°C; 0.5 h;
参考文献
Allergan Sales, Inc.
Patent: US6344561 B2, 2002 ;
Location in patent: Page column 111 ;
反应条件
n-butyllithium in tetrahydrofuran
addn. of BuLi to thiophene (-30°C), then addn. of ZnCl2 soln. (-30°C), warming to 20°C, (during 30 min);
参考文献
Tellier, Frederique; Sauvetre, Raymond; Normant, Jean-F.
Journal of Organometallic Chemistry, 1985 , vol. 292, p. 19 - 28
反应条件
(NH4)2Ce(NO3)5; acetic anhydride
T=25°C; 17 h;
参考文献
Tanemura, Kiyoshi; Suzuki, Tsuneo; Nishida, Yoko; Satsumabayashi, Koko; Horaguchi, Takaaki
Journal of Chemical Research - Part S, 2003 , # 8 p. 497 - 499
反应条件
hydrogenchloride; sodium hydroxide; sodium nitrite
参考文献
Buu-Hoi; Hoan
Recueil des Travaux Chimiques des Pays-Bas, 1950 , vol. 69, p. 1455,1466
