3-乙酰基-4-氧代戊酸乙酯合成路线 （共 18 条）
参考文献
March
Annales de Chimie (Cachan, France), 1902 , vol. <7> 26, p. 305
Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1901 , vol. 132, p. 697
参考文献
March
Annales de Chimie (Cachan, France), 1902 , vol. <7> 26, p. 305
Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1901 , vol. 132, p. 697
反应条件
1: acetic acid / 3 h / 20 °C 2: lithium hydroxide hydrate / methanol / 18 h / 20 °C View Scheme
参考文献
Rackham, Mark D.; Brannigan, James A.; Rangachari, Kaveri; Meister, Stephan; Wilkinson, Anthony J.; Holder, Anthony A.; Leatherbarrow, Robin J.; Tate, Edward W.
Journal of Medicinal Chemistry, 2014 , vol. 57, # 6 p. 2773 - 2788
参考文献
March
Annales de Chimie (Cachan, France), 1902 , vol. <7> 26, p. 305
Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1901 , vol. 132, p. 697
反应条件
1: hydroxylamine hydrochloride; potassium carbonate / ethanol / 3 h / 78 °C 2: lithium hydroxide hydrate / methanol / 18 h / 20 °C View Scheme
参考文献
Rackham, Mark D.; Brannigan, James A.; Rangachari, Kaveri; Meister, Stephan; Wilkinson, Anthony J.; Holder, Anthony A.; Leatherbarrow, Robin J.; Tate, Edward W.
Journal of Medicinal Chemistry, 2014 , vol. 57, # 6 p. 2773 - 2788
反应条件
sodium acetate; acetic acid
T=55 - 105°C; 0.5 h;
参考文献
Sugen, Inc.
Patent: US2004/266843 A1, 2004 ;
Location in patent: Page 13 ;
反应条件
sodium acetate; acetic acid; zinc
24 h; Heatingadding at 90 to 95 deg C, 2.5 h;
参考文献
Holmes, Darren L.; Lightner, David A.
Tetrahedron, 1995 , vol. 51, # 6 p. 1607 - 1622
反应条件
acetic acid; zinc
T=90 - 95°C; Knorr pyrrole synthesis; 2 h;
参考文献
Singh, Vandana; Baqi, Abdul
Journal of the Indian Chemical Society, 2002 , vol. 79, # 8 p. 701 - 702
