1,1-二甲氧基-N,N-二甲基乙胺合成路线 （共 46 条）
参考文献
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), , p. 663 - 668
反应条件
in toluene
5 h; Heating;
参考文献
Stanovnik, Branko; Stimac, Anton; Tisler, Miha; Vercek, Bojan
Journal of Heterocyclic Chemistry, 1982 , vol. 19, p. 577 - 583
反应条件
in DMF (N,N-dimethyl-formamide)
T=20 - 100°C; 16.5833 h;
参考文献
F. HOFFMANN-LA ROCHE AG
Patent: WO2005/5395 A2, 2005 ;
Location in patent: Page 75 ;
WO 2005/005395 A2
反应条件
in xylene
18 h; Heating;
参考文献
Fleet, G. W. J.; Gough, M. J.; Shing, T. K. M.
Tetrahedron Letters, 1983 , vol. 24, # 34 p. 3661 - 3664
反应条件
1: T=120°C; 2 h;
2: With sodium hydroxide; hydroxylamine hydrochloride; acetic acid in 1,4-dioxane; water
T=20 - 90°C; 3.5 h;
3: With sodium hydrogencarbonate in water
pH=9;
参考文献
GLAXO GROUP LIMITED
Patent: WO2005/14571 A1, 2005 ;
Location in patent: Page/Page column 30-31 ;
WO 2005/014571 A1
反应条件
in acetonitrile
Heating;
参考文献
Meriem, Abdelkader; Majoral, Jean-Pierre; Revel, Monique; Navech, Jacques
Tetrahedron Letters, 1983 , vol. 24, # 19 p. 1975 - 1978
参考文献
Randles, K. R.; Storr, R. C.
Tetrahedron Letters, 1987 , vol. 28, # 45 p. 5555 - 5558
参考文献
Chorvat, Robert J.; Prodan, Kathleen A.; Adelstein, Gilbert W.; Rydzewski, Robert M.; McLauglin, Kathleen T.; et al.
Journal of Medicinal Chemistry, 1985 , vol. 28, # 9 p. 1285 - 1291
反应条件
0.75 h; Inert atmosphereHeating;
参考文献
Petrov, Alex R.; Daniliuc, Constantin G.; Jones, Peter G.; Tamm, Matthias
Chemistry - A European Journal, 2010 , vol. 16, # 39 p. 11804 - 11808
参考文献
Chen; Dagnino R.; McCarthy
Journal of Organic Chemistry, 1995 , vol. 60, # 26 p. 8428 - 8430
