1: 1-(4-methylsulfanylphenyl)-1H-imidazole With n-butyllithium in tetrahydrofuran; hexane T=-78°C; 0.25 h; 2: cyclohexanone in tetrahydrofuran; hexane T=-78°C; 0.5 h;

1.1: n-BuLi / tetrahydrofuran; hexane / 0.25 h / -78 °C 1.2: 50 percent / tetrahydrofuran; hexane / 0.5 h / -78 °C 2.1: 91 percent / Oxone(R) / H2O; methanol / 1 h / 20 °C View Scheme

triphenyl-arsane; cesium fluoride; palladium diacetate in N,N-dimethyl-formamide T=140°C; 116 h;