3,4,5-三甲氧基苯甲酸甲酯合成路线 （共 184 条）
反应条件
lithium aluminium tetrahydride; dipyridinium dichromate 1.) THF, 2.) CH2Cl2; Yield given. Multistep reaction;
参考文献
Ishii; Ishikawa; Deushi; et al.
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 9 p. 3024 - 3038
反应条件
1: 70 percent / LAH / tetrahydrofuran 2: 80 percent / PBr3, triethylamine / CCl4 / 1) 1h, 0 degC 2) 3h, roomtemp. View Scheme
参考文献
Parihar, Swati; Kumar, Amit; Chaturvedi, Amit K.; Sachan, Naresh Kumar; Luqman, Suaib; Changkija, Bendangla; Manohar, Murli; Prakash, Om; Chanda; Khan, Feroz; Chanotiya; Shanker, Karuna; Dwivedi, Anila; Konwar, Rituraj; Negi, Arvind S.
Journal of Steroid Biochemistry and Molecular Biology, 2013 , vol. 137, p. 332 - 344
反应条件
boron trichloride in dichloromethane 5 h; Ambient temperature;
参考文献
Carvalho, Christopher F.; Russo, Albert V.; Sargent, Melvyn V.
Australian Journal of Chemistry, 1985 , vol. 38, # 5 p. 777 - 792
反应条件
1: acetic acid anhydride; nitric acid 2: alcoholic KOH-solution View Scheme
参考文献
Williams,K.I.H. et al.
Journal of the American Chemical Society, 1960 , vol. 82, p. 3982 - 3988
反应条件
1.1: magnesium / diethyl ether / Heating 1.2: diethyl ether / Heating 2.1: BF3*Et2O; NaBO3*4H2O / tetrahydrofuran / 20 °C View Scheme
参考文献
Terazzi, Emmanuel; Guenee, Laure; Morgantini, Pierre-Yves; Bernardinelli, Gerald; Donnio, Bertrand; Guillon, Daniel; Piguet, Claude
Chemistry - A European Journal, 2007 , vol. 13, # 6 p. 1674 - 1691
反应条件
sulfuric acid 1.) 40 deg C, 8 h, 2.) 20 deg C, 12 h;
参考文献
Battersby, Alan R.; Bhatnagar, Akil K.; Hackett, Peter; Thornber, Craig W.; Staunton, James
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981 , p. 2002 - 2009
反应条件
lithium aluminium tetrahydride; hydrogen; palladium on activated charcoal 1.) Et2O; 2.) ethanol, 1 atm; Multistep reaction;
参考文献
Cambie, Richard C.; Craw, Peter A.; Rutledge, Peter S.; Woodgate, Paul D.
Australian Journal of Chemistry, 1988 , vol. 41, # 6 p. 897 - 918
反应条件
(i) LiAlH4, THF, (ii) /BRN= 635994/, aq. NaOH; Multistep reaction;
参考文献
Sugihara,H. et al.
Justus Liebigs Annalen der Chemie, 1972 , vol. 763, p. 109 - 120
反应条件
1: lithium aluminium tetrahydride / tetrahydrofuran 2: thionyl chloride / dichloromethane 3: potassium carbonate / dimethyl sulfoxide / 6 h / 50 °C 4: sodium chloride / dimethyl sulfoxide / 5 h / |Reflux View Scheme
参考文献
Zheng, Cheng; Guo, Yibing; Meng, Ying; Dou, Sufeng; Shao, Jian; Yang, Yumin
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2013 , vol. 52, # 5 p. 654 - 664
反应条件
water in methanol T=45°C; Reflux;
参考文献
Bao, Kai; Zhang, Weige; Bu, Xiujuan; Song, Zhichun; Zhang, Liang; Cheng, Maosheng
Chemical Communications, 2008 , # 42 p. 5429 - 5431
