4,4-二甲基-2-苯基-2-噁唑啉合成路线 （共 73 条）
反应条件
sodium iodide in butanone T=56°C; 19 h;
参考文献
Tetrahedron Letters, , vol. 39, # 24 p. 4275 - 4276
反应条件
1: 60 percent / nitromethane / 12 h / 60 - 70 °C 2: 40 percent / acetonitrile / RT, 2 h, then reflux, 8 h View Scheme
参考文献
Tetrahedron, , vol. 42, # 5 p. 1449 - 1460
反应条件
1: 65 percent / 4 h / Heating 2: 60 percent / nitromethane / 12 h / 60 - 70 °C 3: 40 percent / acetonitrile / RT, 2 h, then reflux, 8 h View Scheme
参考文献
Tetrahedron, , vol. 42, # 5 p. 1449 - 1460
反应条件
tetrakis(triphenylphosphine) palladium(0)
参考文献
Kosugi, Masanori; Fukiage, Akio; Takayanagi, Mitsuhiro; Sano, Hiroshi; Migita, Toshihiko; Satoh, Mitsuo
Chemistry Letters, 1988 , # 9 p. 1351 - 1354
反应条件
in ethanol 20 h; Ambient temperature;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 2328 - 2332
反应条件
1: 96 percent 2: 75 percent / Heating View Scheme
参考文献
Journal of Chemical Research, Miniprint, , # 3 p. 901 - 924
反应条件
Lanthanum chloride; n-butyllithium 1) toluene, 0 deg C, 15 min then 0 to 100 deg C, 2) toluene, reflux, 12 h; Yield given. Multistep reaction;
参考文献
Tetrahedron Letters, , vol. 38, # 40 p. 7019 - 7020
反应条件
1.1: n-BuLi / hexane; tetrahydrofuran / 3.5 h 1.2: 58 percent / cuprous bromide / hexane; tetrahydrofuran / 1.5 h / 0 °C 2.1: dimethylsulfoxide / 20 °C 3.1: 2.54 g / NaOH / H2O / 8 h / Heating 4.1: diethyl cyanophosphonate / dimethylformamide / 0.5 h / 0 °C 4.2: 39 percent / Et3N / dimethylformamide / 2 h / 0 °C 5.1: 4 percent / tetraethylammonium tosylate / dimethylformamide / 60 °C / Electrolysis View Scheme
参考文献
Ozaki, Shigeko; Adachi, Masashi; Sekiya, Sayaka; Kamikawa, Rie
Journal of Organic Chemistry, 2003 , vol. 68, # 11 p. 4586 - 4589
反应条件
1: HCl gas / diethyl ether / 0.17 h 2: 80 percent / acetonitrile / RT, 2 h, then reflux, 4 h View Scheme
参考文献
Singh, Harjit; Sarin, Rakesh
Tetrahedron, 1986 , vol. 42, # 5 p. 1449 - 1460
反应条件
1: 1.) BuLi / 1.) THF, -45 deg C, 2.) -100 deg C 2: 5percent aq. HCl / Heating; overnight View Scheme
参考文献
Edgar; Bradsher
Journal of Organic Chemistry, 1982 , vol. 47, # 8 p. 1585 - 1587
