反-3(3-吡啶基)烯丙酸合成路线 （共 32 条）
反应条件
piperidine T=85°C; 6 h; Ionic liquid;
参考文献
Journal of Chemical Research, , vol. 35, # 12 p. 723 - 725
反应条件
1: With potassium hydroxide in N,N-dimethyl-formamide T=20°C; 4 h; 2: With ammonium chloride in water
参考文献
Synthetic Communications, , vol. 31, # 7 p. 1007 - 1011
反应条件
lithium hydroxide in 1,4-dioxane 2 h;
参考文献
Journal of Medicinal Chemistry, , vol. 36, # 3 p. 320 - 330
反应条件
potassium hydroxide in ethanol; water T=25°C; 20 h;
参考文献
Journal of Medicinal Chemistry, , vol. 57, # 3 p. 770 - 792
反应条件
piperidine; pyridine Doebner Modification;
参考文献
Angewandte Chemie - International Edition, , vol. 52, # 21 p. 5548 - 5551
Angew. Chem., , vol. 125, # 21 p. 5658 - 5661,4
反应条件
ammonium acetate in butan-1-ol Rodionov reaction; Heating;
参考文献
Russian Journal of General Chemistry, , vol. 75, # 7 p. 1113 - 1124
反应条件
1: palladium diacetate; triphenylphosphine; potassium carbonate / N,N-dimethyl-formamide / 20 h / 130 °C / |Inert atmosphere 2: potassium hydroxide / ethanol; water / 20 h / 25 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 57, # 3 p. 770 - 792
反应条件
piperidine; potassium acetate T=180 - 190°C;
参考文献
Recueil des Travaux Chimiques des Pays-Bas, , vol. 74, p. 1049,1053
参考文献
Journal of the American Pharmaceutical Association (1912-1977), , vol. 43, p. 163
参考文献
Chemische Berichte, , vol. 91, p. 1621,1629
