2-乙氧基-5-(4-甲基-1 哌嗪磺酰基)苯甲酸合成路线 （共 5 条）
反应条件
in N,N-dimethyl-formamide pH=7.4; aq. phosphate bufferHeating;
参考文献
Park, Hee-Moon; Chang, Bong-Jun; Jin, Hangkyo; Kim, Jeong-Hoon
Asian Journal of Chemistry, 2012 , vol. 24, # 9 p. 4163 - 4165
反应条件
sodium hydroxide in water
T=10 - 20°C; 2.08333 h;
参考文献
Dale, David J.; Dunn, Peter J.; Golightly, Clare; Hughes, Michael L.; Levett, Philip C.; Pearce, Andrew K.; Searle, Patricia M.; Ward, Gordon; Wood, Albert S.
Organic Process Research and Development, 2000 , vol. 4, # 1 p. 17 - 22
参考文献
Pfizer Inc.
Patent: US6723719 B1, 2004 ;
Location in patent: Page column 64 ;
参考文献
Pfizer Inc.
Patent: US5955611 A1, 1999 ;
反应条件
1: thionyl chloride; chlorosulfonic acid / 20 °C
2: sodium hydroxide / water / 2.08 h / 10 - 20 °C
View Scheme
参考文献
Dale, David J.; Dunn, Peter J.; Golightly, Clare; Hughes, Michael L.; Levett, Philip C.; Pearce, Andrew K.; Searle, Patricia M.; Ward, Gordon; Wood, Albert S.
Organic Process Research and Development, 2000 , vol. 4, # 1 p. 17 - 22
