二苯基-吡啶-3-基-甲醇合成路线 （共 8 条）
反应条件
1: 3-bromo-pyridine With n-butyllithium in tetrahydrofuran; hexane T=-90°C; 0.5 h; 2: benzophenone in tetrahydrofuran; hexane T=-90°C; 3.5 h;
参考文献
Anderson; Seeger
Journal of the American Chemical Society, 1949 , vol. 71, p. 343
反应条件
1: 3-bromo-pyridine With isopropylmagnesium chloride in tetrahydrofuran T=20°C; Substitution; 1 h; 2: benzophenone in tetrahydrofuran T=20°C; Substitution; 18 h;
参考文献
Trecourt, Francois; Breton, Gilles; Bonnet, Veronique; Mongin, Florence; Marsais, Francis; Queguiner, Guy
Tetrahedron, 2000 , vol. 56, # 10 p. 1349 - 1360
反应条件
diethyl ether T=-50 - -35°C;
参考文献
Wibaut et al.
Recueil des Travaux Chimiques des Pays-Bas, 1951 , vol. 70, p. 1054,1061
反应条件
1: 3-bromo-pyridine; n-butyllithium in toluene T=-50°C; 2: benzophenone in tetrahydrofuran T=-50 - -15°C;
参考文献
Cai, Dongwei; Larsen, Robert D; Reider, Paul J
Tetrahedron Letters, 2002 , vol. 43, # 23 p. 4285 - 4287
反应条件
in diethyl ether T=-10°C; 2 h;
参考文献
Tzerpos, Nikolaos I.; Zarkadis, Antonios K.; Kreher, Richard P.; Repas, Liesel; Lehnig, Manfred
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1995 , # 4 p. 755 - 762
参考文献
Fuson; Miller
Journal of the American Chemical Society, 1957 , vol. 79, p. 3477,3480
参考文献
Kasuya
Yakugaku Zasshi, 1958 , vol. 78, p. 509
Chem.Abstr., 1958 , p. 17196
反应条件
sodium tetrahydroborate; trifluoroacetic acid in dichloromethane
T=20°C;
参考文献
Nutaitis, Charles F.; Greshock, Thomas J.; Houghton, Stephen R.; Moran, Lynn N.; Walter, Melissa A.
Organic Preparations and Procedures International, 2002 , vol. 34, # 3 p. 332 - 335
