5-(2-硝基苯)呋喃醛合成路线 （共 14 条）
反应条件
1: 2-nitro-aniline With hydrogenchloride; sodium nitrite in water 2: furfural With copper dichloride in water Meerwein reaction; 4 h;
参考文献
Synthetic Communications, , vol. 35, # 3 p. 333 - 340
反应条件
tetrakis(triphenylphosphine) palladium(0); potassium carbonate in ethanol; toluene Suzuki coupling; 5 h; Heating;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 12, # 19 p. 2681 - 2683
反应条件
triethylamine; palladium on activated charcoal in ethanol T=60°C; Suzuki cross-coupling reaction; 16 h;
参考文献
Synthesis, , # 11 p. 1681 - 1685
反应条件
bis-triphenylphosphine-palladium(II) chloride; sodium carbonate in ethylene glycol dimethyl ether; ethanol; water T=50°C; Suzuki reaction; 3 h;
参考文献
Bioorganic and Medicinal Chemistry, , vol. 11, # 5 p. 663 - 673
反应条件
bis-triphenylphosphine-palladium(II) chloride in ethylene glycol dimethyl ether T=50°C; Stille reaction; 1 h;
参考文献
Bioorganic and Medicinal Chemistry, , vol. 11, # 5 p. 663 - 673
反应条件
borane dimethyl sulfide complex in tetrahydrofuran T=50 - 60°C; 2.5 h; Inert atmosphere;
参考文献
ACS Medicinal Chemistry Letters, , vol. 4, # 5 p. 475 - 480
反应条件
1.1: n-BuLi / dimethylformamide; hexane / 2 h / -20 °C 1.2: B(O-iPr)3 / dimethylformamide; hexane / -20 - 20 °C 1.3: AcOH; H2O / dimethylformamide; hexane / 20 °C 2.1: 84 percent / Et3N / 10 percent Pd/C / ethanol / 16 h / 60 °C View Scheme
参考文献
Synthesis, , # 11 p. 1681 - 1685
反应条件
tetrakis(triphenylphosphine) palladium(0); potassium carbonate in ethanol; toluene T=100°C; Suzuki coupling; 4 h; Inert atmosphere;
参考文献
Organic and Biomolecular Chemistry, , vol. 10, # 36 p. 7402 - 7417
反应条件
CuCl2·2H2O in water; acetone T=20°C; 12 h;
参考文献
Journal of Agricultural and Food Chemistry, , vol. 61, # 46 p. 10858 - 10863
反应条件
1: 2-nitro-aniline With hydrogenchloride; sodium nitrite in water 0.166667 h; Cooling with ice; 2: furan-2-carboxylic acid With copper dichloride in water; acetone
参考文献
ACS Medicinal Chemistry Letters, , vol. 4, # 5 p. 475 - 480
