2-氨基-5-苯基-1,3,4-噻二唑合成路线 （共 74 条）
反应条件
pyridine in methanol Heating;
参考文献
Russian Chemical Bulletin, , vol. 45, # 5 p. 1185 - 1188
反应条件
1: 53 percent / dimethylformamide / 20 h / Ambient temperature 2: 89 percent / CHCl3 / 1 h / Heating 3: aq.HCl / ethanol / 1 h / Heating View Scheme
参考文献
Journal of Heterocyclic Chemistry, , vol. 21, p. 1689 - 1698
反应条件
1: hydrazine hydrate / ethanol / Reflux 2: hydrogenchloride / water / Heating 3: sulfuric acid View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 16 p. 4919 - 4923
反应条件
1: hydrogenchloride / water / Heating 2: sulfuric acid View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 16 p. 4919 - 4923
反应条件
anhydrous iron chloride; anhydrous trisodium citrate; citric acid in water T=80 - 90°C; 0.75 h;
参考文献
Archiv der Pharmazie, , vol. 346, # 11 p. 819 - 831
反应条件
1: 3 N NaOH / H2O / 0.17 h / Ambient temperature 2: 65 percent / 2N AcOH / ethanol 3: 75 percent / 3 N HCl / ethanol / 0.5 h / Heating View Scheme
参考文献
Tetrahedron, , vol. 37, p. 1429 - 1436
反应条件
1: 89 percent / CHCl3 / 1 h / Heating 2: aq.HCl / ethanol / 1 h / Heating View Scheme
参考文献
Journal of Heterocyclic Chemistry, , vol. 21, p. 1689 - 1698
反应条件
1.1: sulfuric acid / 10 h / Reflux 2.1: hydrazine hydrate / 0 °C 3.1: hydrogenchloride / water / Reflux 4.1: sulfuric acid / 2 h / 20 °C 4.2: 2 h / Cooling with ice View Scheme
参考文献
Organic and Biomolecular Chemistry, , vol. 10, # 9 p. 1785 - 1794
反应条件
T=200°C; 0.333333 h;
参考文献
Journal of Heterocyclic Chemistry, , vol. 21, p. 1689 - 1698
反应条件
in N,N-dimethyl-formamide 3 h; Heating;
参考文献
Tetrahedron, , vol. 42, # 5 p. 1449 - 1460
Heterocycles, , vol. 22, # 5 p. 1101 - 1104
