2-溴-4-甲基-6-硝基苯酚合成路线 (共 22 条)
反应条件
sodium nitrate; sulfuric acid in water T=-5 - 25°C;
参考文献
Jiangsu Hengrui Medicine Co., Ltd.; Shanghai Hengrui Pharmaceutical Co. Ltd.
Patent: EP2236500 A1, 2010 ;
Location in patent: Page/Page column 31 ;
反应条件
sodium nitrite in acetic acid
参考文献
Hardcastle, Ian R.; Hunter, Ruth F.; Quayle, Peter; Edwards, Philip N.
Tetrahedron Letters, 1994 , vol. 35, # 22 p. 3805 - 3808
反应条件
N,N,N-trimethyl-1-phenylmethanaminium tribromide; calcium carbonate in methanol; dichloromethane
参考文献
Kakinami; Suenaga; Yamaguchi; Okamoto; Kajigaeshi
Bulletin of the Chemical Society of Japan, 1989 , vol. 62, # 10 p. 3373 - 3375
反应条件
1: iron; glacial acetic acid / durch Bromieren 2: concentrated alcohol View Scheme
参考文献
Justus Liebigs Annalen der Chemie, , vol. 311, p. 366 Anm.
反应条件
bromine; silver nitrate in acetonitrile 2 h; Ambient temperature;
参考文献
Canadian Journal of Chemistry, , vol. 67, p. 104 - 108
反应条件
acetic acid T=20°C; 12 h;
参考文献
Australian Journal of Chemistry, , vol. 37, # 1 p. 55 - 64
反应条件
nitric acid; acetic anhydride T=-40°C; 0.666667 h; Title compound not separated from byproducts;
参考文献
Canadian Journal of Chemistry, , vol. 65, p. 1233 - 1240
反应条件
nitric acid T=-40°C; 0.666667 h;
参考文献
Canadian Journal of Chemistry, , vol. 65, p. 1233 - 1240
参考文献
Justus Liebigs Annalen der Chemie, , vol. 311, p. 366 Anm.
参考文献
Justus Liebigs Annalen der Chemie, , vol. 341, p. 310
Journal fuer Praktische Chemie (Leipzig), , vol. <2> 61, p. 566
Chemische Berichte, , vol. 34, p. 256