5-甲酰基-呋喃并[2,3-b]吡啶合成路线 （共 5 条）
反应条件
in water; dimethyl sulfoxide
参考文献
Merck and Co., Inc.
Patent: US5705515 A1, 1998 ;
US 5705515 A
反应条件
Dess-Martin periodane in dichloromethane
参考文献
ACTELION PHARMACEUTICALS LTD
Patent: WO2008/132679 A1, 2008 ;
Location in patent: Page/Page column 88 ;
WO 2008/132679 A1
反应条件
diisobutylaluminium hydride in dichloromethane T=-50°C; 0.25 h;
参考文献
Yamaguchi, Seiji; Kurosaki, Masahide; Yokoyama, Hajime; Hirai, Yoshiro; Shiotani, Shunsaku
Journal of Heterocyclic Chemistry, 1998 , vol. 35, # 6 p. 1305 - 1307
反应条件
1: 1.) 35 percent aq. HCl, NaNO2, 2.) aq. NaCN / 1.) from 0 deg C to 5 deg C, 15 min, 2.) benzene, RT, 3 h 2: 33 percent / DIBAL-H / CH2Cl2 / 0.25 h / -50 °C View Scheme
参考文献
Yamaguchi, Seiji; Kurosaki, Masahide; Yokoyama, Hajime; Hirai, Yoshiro; Shiotani, Shunsaku
Journal of Heterocyclic Chemistry, 1998 , vol. 35, # 6 p. 1305 - 1307
反应条件
1: Al(Hg), water / diethyl ether / 3 h / Ambient temperature 2: 1.) 35 percent aq. HCl, NaNO2, 2.) aq. NaCN / 1.) from 0 deg C to 5 deg C, 15 min, 2.) benzene, RT, 3 h 3: 33 percent / DIBAL-H / CH2Cl2 / 0.25 h / -50 °C View Scheme
参考文献
Yamaguchi, Seiji; Kurosaki, Masahide; Yokoyama, Hajime; Hirai, Yoshiro; Shiotani, Shunsaku
Journal of Heterocyclic Chemistry, 1998 , vol. 35, # 6 p. 1305 - 1307
