1-Boc-4-环己基氨基哌啶合成路线 (共 2 条)
反应条件
sodium cyanoborohydride in tetrahydrofuran; methanol T=20°C;
参考文献
SANOFI-AVENTIS
Patent: US2007/191364 A1, 2007 ;
Location in patent: Page/Page column 16 ;
反应条件
1: With sodium acetate; acetic acid in tetrahydrofuran T=20°C; 3 h; 2: With sodium tris(acetoxy)borohydride in tetrahydrofuran T=20°C; 16 h; 3: With water in tert-butyl methyl ether
参考文献
SOLVAY PHARMACEUTICALS GmbH
Patent: US2007/149512 A1, 2007 ;
Location in patent: Page/Page column 17 ;