(R)-(-)-扁桃酸甲酯合成路线 （共 107 条）
反应条件
in methanol T=-10°C; 6 h; Resolution of racemateSealed tube; enantioselective reaction;
参考文献
Chemical Communications, , vol. 49, # 74 p. 8253 - 8255
反应条件
anhydrous magnesium perchlorate in acetonitrile-D3 T=0°C; 0.1 h; enantiomers of 1,4-dihydropyridines; var. reagents, times, and temp.; Product distributionMechanism;
参考文献
Journal of Organic Chemistry, , vol. 54, # 6 p. 1313 - 1320
反应条件
lithium hydroxide; dihydrogen peroxide 1.) THF, water; Multistep reaction. Yields of byproduct given;
参考文献
Tetrahedron Letters, , vol. 35, # 31 p. 5621 - 5624
反应条件
1: 1.) trifluoroacetic anhydride, pyridine, 2.) aq. LiOH / 1.) CH2Cl2, 0 deg C, 15 min, 2.) THF, from 0 deg C to RT 2: 90 percent / Hg(OCOCF3)2, BF3*OEt2 View Scheme
参考文献
Journal of the Chemical Society, Chemical Communications, , # 14 p. 1653 - 1654
反应条件
phosphate buffer 1.) Rhodococcus botanica ATCC 21197, 30 deg C, 48 h; Yield given. Multistep reaction;
参考文献
Agricultural and Biological Chemistry, , vol. 55, # 7 p. 1877 - 1881
反应条件
in methanol; toluene
参考文献
Tetrahedron Asymmetry, , vol. 20, # 23 p. 2704 - 2708
反应条件
anhydrous magnesium perchlorate; (S)-N,N-dimethylphenylalaninol derivative (chiral catalyst) in acetonitrile T=65°C; 120 h; other reduction reagent-catalyst-combination on silca, enantioselectivity (asymmetric induction); Product distribution;
参考文献
Bulletin de la Societe Chimique de France, , # 5 p. 721 - 729
反应条件
Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Tetrahedron Asymmetry, , vol. 7, # 10 p. 2939 - 2956
反应条件
anhydrous magnesium perchlorate in acetonitrile 72 h; other reduction reagents, other temperatures, other solvents, other Mg(ClO4)2 concentrations; Product distribution;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 867 - 872
反应条件
1: Ag2O 2: aq. H2SO4 View Scheme
参考文献
Barth,G. et al.
Journal of the American Chemical Society, 1970 , vol. 92, p. 875 - 886
