醋酸(Z)-11-十四烯酯合成路线 （共 59 条）
反应条件
1: 28 percent / DMSO, NaH / tetrahydrofuran / 0.5 h
2: pyridine
View Scheme
参考文献
Horiike; Tanouchi; Hirano
Agricultural and Biological Chemistry, 1980 , vol. 44, # 2 p. 257 - 261
反应条件
1: 1.) B2H6, 2.) H2O2/3N NaOH / 1.) diglyme, 5h, 2.) room temperature, overnight
2: 85 percent / PBr3 / benzene / 5 h / Ambient temperature
3: 22 g / acetonitrile / 8 h / Heating
4: 1.) potassium tert-butanolate / 1.) DMF, 20 deg C, 3h, 2.) 5h
5: LiAlH4 / diethyl ether / 3 h / Heating
6: pyridine / 10 h / Ambient temperature
View Scheme
参考文献
Dzhemilev, U. M.; Balezina, G. G.; Volkova, L. A.; Krivonogov, V. P.; Tolstikov, G. A.
Chemistry of Natural Compounds, 1980 , vol. 16, # 1 p. 82 - 85
Khimiya Prirodnykh Soedinenii, 1980 , vol. 16, # 1 p. 97 - 102
反应条件
1: 22 g / acetonitrile / 8 h / Heating
2: 1.) potassium tert-butanolate / 1.) DMF, 20 deg C, 3h, 2.) 5h
3: LiAlH4 / diethyl ether / 3 h / Heating
4: pyridine / 10 h / Ambient temperature
View Scheme
参考文献
Dzhemilev, U. M.; Balezina, G. G.; Volkova, L. A.; Krivonogov, V. P.; Tolstikov, G. A.
Chemistry of Natural Compounds, 1980 , vol. 16, # 1 p. 82 - 85
Khimiya Prirodnykh Soedinenii, 1980 , vol. 16, # 1 p. 97 - 102
反应条件
1: 1.) B2H6, 2.) H2O2/3N NaOH / 1.) diglyme, 5h, 2.) room temperature, overnight
2: H2/RaNi / ethyl acetate / 4 h / 80 °C / 76000.1 Torr
3: 85 percent / PBr3 / benzene / 5 h / Ambient temperature
4: 22 g / acetonitrile / 8 h / Heating
5: 1.) potassium tert-butanolate / 1.) DMF, 20 deg C, 3h, 2.) 5h
6: LiAlH4 / diethyl ether / 3 h / Heating
7: pyridine / 10 h / Ambient temperature
View Scheme
参考文献
Dzhemilev, U. M.; Balezina, G. G.; Volkova, L. A.; Krivonogov, V. P.; Tolstikov, G. A.
Chemistry of Natural Compounds, 1980 , vol. 16, # 1 p. 82 - 85
Khimiya Prirodnykh Soedinenii, 1980 , vol. 16, # 1 p. 97 - 102
反应条件
1: 1.) potassium tert-butanolate / 1.) DMF, 20 deg C, 3h, 2.) 5h
2: LiAlH4 / diethyl ether / 3 h / Heating
3: pyridine / 10 h / Ambient temperature
View Scheme
参考文献
Dzhemilev, U. M.; Balezina, G. G.; Volkova, L. A.; Krivonogov, V. P.; Tolstikov, G. A.
Chemistry of Natural Compounds, 1980 , vol. 16, # 1 p. 82 - 85
Khimiya Prirodnykh Soedinenii, 1980 , vol. 16, # 1 p. 97 - 102
反应条件
1: H2/RaNi / ethyl acetate / 4 h / 80 °C / 76000.1 Torr
2: 85 percent / PBr3 / benzene / 5 h / Ambient temperature
3: 22 g / acetonitrile / 8 h / Heating
4: 1.) potassium tert-butanolate / 1.) DMF, 20 deg C, 3h, 2.) 5h
5: LiAlH4 / diethyl ether / 3 h / Heating
6: pyridine / 10 h / Ambient temperature
View Scheme
参考文献
Dzhemilev, U. M.; Balezina, G. G.; Volkova, L. A.; Krivonogov, V. P.; Tolstikov, G. A.
Chemistry of Natural Compounds, 1980 , vol. 16, # 1 p. 82 - 85
Khimiya Prirodnykh Soedinenii, 1980 , vol. 16, # 1 p. 97 - 102
反应条件
1: 90 percent / H2SO4 / 24 h / Heating
2: 70 percent / PCC, NaOAc / CH2Cl2 / 24 h / Ambient temperature
3: n-BuLi / toluene / 2 h / 25 °C
4: lithium aluminium hydride / tetrahydrofuran / 4 h / Heating
5: pyridine / 24 h / 25 °C
View Scheme
参考文献
Vinczer, Peter; Juvancz, Zoltan; Novak, Lajos; Szantay, Csaba
Acta Chimica Hungarica, 1988 , vol. 125, # 6 p. 797 - 820
反应条件
1: 92 percent / 2N NaOH / 5 h / Heating
2: 90 percent / H2SO4 / 24 h / Heating
3: 70 percent / PCC, NaOAc / CH2Cl2 / 24 h / Ambient temperature
4: n-BuLi / toluene / 2 h / 25 °C
5: lithium aluminium hydride / tetrahydrofuran / 4 h / Heating
6: pyridine / 24 h / 25 °C
View Scheme
参考文献
Vinczer, Peter; Juvancz, Zoltan; Novak, Lajos; Szantay, Csaba
Acta Chimica Hungarica, 1988 , vol. 125, # 6 p. 797 - 820
反应条件
1: n-BuLi / toluene / 2 h / 25 °C
2: lithium aluminium hydride / tetrahydrofuran / 4 h / Heating
3: pyridine / 24 h / 25 °C
View Scheme
参考文献
Vinczer, Peter; Juvancz, Zoltan; Novak, Lajos; Szantay, Csaba
Acta Chimica Hungarica, 1988 , vol. 125, # 6 p. 797 - 820
反应条件
1.1: hydrogen bromide / benzene / 2.5 h / Reflux
2.1: sulfuric acid / water / 40 °C
3.1: sodium hydride / dimethyl sulfoxide / 20 - 30 °C / Inert atmosphere
3.2: 3 h / 20 °C / Inert atmosphere
4.1: Nessler's reagent / ethanol; water / Cooling with ice
4.2: 4 h / 90 - 125 °C / Inert atmosphere
5.1: acetic acid / Reflux
6.1: Ni-P2/EDA
View Scheme
参考文献
Gansca, Lucia; Andreica, Adriana; Ciotlaus, Irina; Maxim, Sanda; Oprean, Ioan
Revue Roumaine de Chimie, 2011 , vol. 56, # 7 p. 705 - 709
