4-硝基吡唑合成路线

参考文献

CELON PHARMA S.A.; DZWONEK, Karolina; MROCZKIEWICZ, Michal; STEFANIAK, Filip; WIECZOREK, Maciej; DUBIEL, Krzysztof; LAMPARSKA-PRZYBYSZ, Monika
Patent: WO2014/20531 A1, 2014 ;
Location in patent: Page/Page column 15 ;

2075-46-94-硝基吡唑+

768-93-41-吲哚金刚烷

49764-18-3+

768-95-61-金刚烷醇

参考文献

Tsypin; Pevzner; Golod
Russian Journal of Organic Chemistry, 2001 , vol. 37, # 12 p. 1762 - 1766

2075-46-94-硝基吡唑

28466-26-44-氨基吡唑

参考文献

Park, Sungho; Lee, In Su; Park, Jaiwook
Organic and Biomolecular Chemistry, 2013 , vol. 11, # 3 p. 395 - 399

2075-46-94-硝基吡唑+

64-19-7醋酸

28466-26-44-氨基吡唑

参考文献

Knorr
Chemische Berichte, 1904 , vol. 37, p. 3501

2075-46-94-硝基吡唑+

100-39-0溴化苄

88095-61-81-苄基-4-硝基-1H-吡唑

参考文献

US2010/120874 A1, ;

Page/Page column 27-28 ;

2075-46-94-硝基吡唑+

75-03-6碘乙烷

876343-24-74-氨基-1-乙基吡唑

参考文献

CELLZOME LIMITED; RAMSDEN, Nigel; HARRISON, Richard John; OXENFORD, Sally; BELL, Kathryn; PITON, Nelly; DAGOSTIN, Claudio; BOUSSARD, Cyrille; RATCLIFFE, Andrew
Patent: WO2011/48082 A1, 2011 ;
Location in patent: Page/Page column 63; 64; 69; 70 ;
WO 2011/048082 A1

2075-46-94-硝基吡唑+

74-88-4甲基碘

54210-32-11-甲基-3-硝基吡唑

参考文献

CELLZOME LIMITED; OXENFORD, Sally; HOBSON, Andrew; OLIVER, Kathryn; RATCLIFFE, Andrew; RAMSDEN, Nigel
Patent: WO2013/17479 A1, 2013 ;
Location in patent: Page/Page column 45 ;
WO 2013/017479 A1

2075-46-94-硝基吡唑+

74-88-4甲基碘

69843-13-61-甲基-4-氨基吡唑

参考文献

CELLZOME LIMITED; HARRISON, Richard, John; OXENFORD, Sally; HOBSON, Andrew; RAMSDEN, Nigel; MILLER, Warren
Patent: WO2011/134831 A1, 2011 ;
Location in patent: Page/Page column 36 ;
WO 2011/134831 A1

67-56-1甲醇+

2075-46-94-硝基吡唑+

150-78-7对苯二甲醚

15791-03-43,3,6,6-四甲氧基-1,4-环己二烯

参考文献

Chauzov; Parchinskii; Sinel'shchikova; Burasov; Ugrak; Parfenov; Petrosyan
Russian Chemical Bulletin, 2002 , vol. 51, # 8 p. 1523 - 1532

2075-46-94-硝基吡唑

103286-54-03-氯-1H-吡唑-4-胺

参考文献

CELLZOME LIMITED; RAMSDEN, Nigel; HARRISON, Richard John; OXENFORD, Sally; BELL, Kathryn; PITON, Nelly; DAGOSTIN, Claudio; BOUSSARD, Cyrille; RATCLIFFE, Andrew
Patent: WO2011/48082 A1, 2011 ;
Location in patent: Page/Page column 115 ;
WO 2011/048082 A1