2-氯-1,4-二甲氧基苯合成路线 （共 31 条）
参考文献
Magnetic Resonance in Chemistry, , vol. 28, p. 315 - 317
反应条件
in trifluoroacetic acid other chlorinating agent, other products; Product distributionMechanism;
参考文献
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), , p. 1529 - 1536
参考文献
Journal of Applied Chemistry, , vol. 3, p. 416
反应条件
1: (i) Na, benzene, (ii) /BRN= 2046890/ 2: H2 / Pd / methanol View Scheme
参考文献
Ehrhart,G.
Chemische Berichte, 1963 , vol. 96, p. 2042 - 2046
反应条件
tris-(dibenzylideneacetone)dipalladium(0); t-Bu Brett Phos; triethylamine in toluene T=110°C; 16 h; Inert atmosphere;
参考文献
Vinogradova, Ekaterina V.; Fors, Brett P.; Buchwald, Stephen L.
Journal of the American Chemical Society, 2012 , vol. 134, # 27 p. 11132 - 11135
反应条件
1: acetic acid; aqueous nitric acid / unter Kuehlung 2: tin (II)-chloride View Scheme
参考文献
Posternak et al.
Helvetica Chimica Acta, 1948 , vol. 31, p. 525,535
反应条件
nitric acid; silica gel in dichloromethane 0.583333 h; Ambient temperature;
参考文献
Tapia, Ricardo; Torres, Glenda; Valderrama, Jaime A.
Synthetic Communications, 1986 , vol. 16, # 6 p. 681 - 688
参考文献
Posternak et al.
Helvetica Chimica Acta, 1948 , vol. 31, p. 525,535
反应条件
hydrogenchloride Heating;
参考文献
Yoo, Choong Leol; Yu, Gui Jun; Yang, Baoxue; Robins, Lori I.; Verkman; Kurth, Mark J.
Bioorganic and Medicinal Chemistry Letters, 2008 , vol. 18, # 8 p. 2610 - 2614
反应条件
18-crown-6 ether; iodine; hexacarbonyl chromium 1.) diglyme, cyclohexane, reflux, 95 h, 2.) benzene, 70 deg C, 3.5 h, 3.) THF, R.T., 30 min; Yield given. Multistep reaction;
参考文献
Fukui; Endo; Oishi
Chemical and Pharmaceutical Bulletin, 1980 , vol. 28, # 12 p. 3639 - 3648
