2,3,4-三甲氧基苯甲醛合成路线 （共 87 条）
反应条件
1: 95.4 percent / 40percent peracetic acid, conc. sulfuric acid / methanol; H2O / 2 h / 20 °C 2: boric acid, acetic acid, methyl borate, H2 / 10percent Pd-C / 4 h / 190 °C / 45600 Torr View Scheme
参考文献
Minami, Norio; Kijima, Shizumasa
Chemical & Pharmaceutical Bulletin, 1980 , vol. 28, # 5 p. 1648 - 1650
反应条件
1: 70.6 percent / AlCl3 / diethyl ether / 72 h / Ambient temperature 2: 72.3 percent / Zn-Hg, conc. HCl / H2O; toluene / 14 h / Heating 3: 1.3 g / ON(SO3K)2, sodium acetate / acetone; H2O / 2 h / Ambient temperature View Scheme
参考文献
Sugihara,H. et al.
Justus Liebigs Annalen der Chemie, 1972 , vol. 763, p. 109 - 120
反应条件
Mexican Bentonite; hydroxylamine hydrochloride 0.25 h; Irradiation;
参考文献
Delgado; Cano; Garcia; Alvarado; Velasco; Alvarez; Rudler
Synthetic Communications, 1992 , vol. 22, # 14 p. 2125 - 2128
反应条件
1: piperidine; pyridine 2: aq. NaOH solution; sodium-amalgam View Scheme
参考文献
Slotta; Heller
Chemische Berichte, 1930 , vol. 63, p. 3029,3043
反应条件
sodium man verseift mit methylalkoholischer Natronlauge und reduziert das Reaktionsprodukt mit Natriumamalgam;
参考文献
Barger; Ewins
Journal of the Chemical Society, 1910 , vol. 97, p. 2260
反应条件
1: NaBH3CN, AcOH / 16 h / Ambient temperature 2: aq. KOH / ethanol / 2.5 h / 130 °C View Scheme
参考文献
Ferte, Jacques; Kuehnel, Jean-Marc; Chapuis, Genevieve; Rolland, Yves; Lewin, Guy; Schwaller, Marc A.
Journal of Medicinal Chemistry, 1999 , vol. 42, # 3 p. 478 - 489
反应条件
boron trichloride in dichloromethane T=0°C; Inert atmosphere;
参考文献
Tanpure, Rajendra P.; Strecker, Tracy E.; Chaplin, David J.; Siim, Bronwyn G.; Trawick, Mary Lynn; Pinney, Kevin G.
Journal of Natural Products, 2010 , vol. 73, # 6 p. 1093 - 1101
反应条件
1: With boron trichloride in dichloromethane T=0°C; 5 h; Inert atmosphere; 2: With water in dichloromethane
参考文献
BAYLOR UNIVERSITY
Patent: US2012/130129 A1, 2012 ;
Location in patent: Page/Page column 12 ;
反应条件
1.1: selenium(IV) oxide; dihydrogen peroxide / tert-butyl alcohol / 1.5 h / 50 °C 2.1: triethylamine / methanol / 0 - 20 °C 3.1: potassium carbonate / acetone / 0 - 20 °C / Inert atmosphere 4.1: trichlorophosphate / 0.33 h / 20 °C 4.2: 6 h / 60 °C 5.1: selenium(IV) oxide; dihydrogen peroxide / tert-butyl alcohol / 2.5 h / 50 °C 6.1: triethylamine / methanol / 0 - 20 °C 7.1: potassium carbonate / acetone / 36 h / 20 °C / Inert atmosphere 8.1: AlCl3, aluminium chloride / dichloromethane / 0 - 20 °C 9.1: lithium hexamethyldisilazane / tetrahydrofuran / -30 - 0 °C / Inert atmosphere 10.1: trifluoroacetic acid / methanol / 24 h / 50 °C View Scheme
参考文献
Chemical Communications, , vol. 47, # 10 p. 2868 - 2870
参考文献
Zaveri, Nurulain; Chao, Wan-Ru
Patent: US2004/29914 A1, 2004 ;
