4-溴-2-氟苯酚合成路线

AMGEN INC.; DRANSFIELD, Paul, John; GONZALEZ LOPEZ DE TURISO, Felix; KOHN, Todd, J.; PATTAROPONG, Vatee; SIMARD, Jillian, L.
Patent: WO2012/3283 A1, 2012 ;
WO 2012/003283 A1

74-96-4溴乙烷+

2105-94-44-溴-2-氟苯酚

115467-08-84-溴-1-乙氧基-2-氟苯

参考文献

MERCK PATENT GMBH
Patent: WO2004/76438 A2, 2004 ;
Location in patent: Page/Page column 129 ;

2105-94-44-溴-2-氟苯酚+

75-03-6碘乙烷

115467-08-84-溴-1-乙氧基-2-氟苯

参考文献

ASTRAZENECA AB; ASTRAZENECA UK LIMITED
Patent: WO2009/1127 A1, 2008 ;
Location in patent: Page/Page column 272 ;
WO 2009/001127 A1

115467-08-84-溴-1-乙氧基-2-氟苯

参考文献

IMPERIAL CHEMICAL INDUSTRIES PLC
Patent: EP240121 B1, 1991 ;

2105-94-44-溴-2-氟苯酚+

16420-13-6二甲基硫代氨基甲酰氯

190648-99-8O-(4-溴-2-氟苯基) 二甲基氨基硫甲酸酯

参考文献

Roche Palo Alto LLC
Patent: US2004/198736 A1, 2004 ;
Location in patent: Page/Page column 90 ;

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