N-(2-苯基苯基)乙酰胺合成路线 （共 68 条）
反应条件
pyridine in dichloromethane
T=0 - 20°C; Friedel Crafts acylation; Inert atmosphere;
参考文献
Xi, Jie; Dong, Qing-Li; Liu, Guan-Sai; Wang, Shaozhong; Chen, Lin; Yao, Zhu-Jun
Synlett, 2010 , # 11 p. 1674 - 1678
反应条件
lithium hydroxide hydrate in dichloromethane
T=0 - 20°C; 2.08333 h;
参考文献
Weitz, Evan A.; Chang, Jennifer Y.; Rosenfield, Adam H.; Pierre, Valerie C.
Journal of the American Chemical Society, 2012 , vol. 134, # 39 p. 16099 - 16102,4
反应条件
acetic anhydride in sodium acetate
参考文献
Abbott Laboratories
Patent: US5362747 A1, 1994 ;
US 5362747 A
反应条件
1H-imidazole; thionyl chloride in tetrahydrofuran
T=25°C; 1 h;
参考文献
Lion, C.; Boukou-Poba, J. P.; Charvy, C.
Bulletin des Societes Chimiques Belges, 1989 , vol. 98, # 8 p. 557 - 566
反应条件
indium; acetic acid in methanol
T=20°C; 1 h;
参考文献
Kim, Byeong Hyo; Han, Rongbi; Piao, Fengyu; Jun, Young Moo; Baik, Woonphil; Lee, Byung Min
Tetrahedron Letters, 2003 , vol. 44, # 1 p. 77 - 79
反应条件
in N,N-dimethyl-formamide
T=130°C; 3 h;
参考文献
THE TEXAS A and M UNIVERSITY SYSTEM
Patent: WO2006/23763 A1, 2006 ;
Location in patent: Page/Page column 12; 13 ;
反应条件
silver hexafluoroantimonate; {RuCl2(1-methyl-4-(1-methylethyl)benzene)}2; copper(II) bis(trifluoromethanesulfonate); silver(l) oxide in tetrahydrofuran
T=110°C; 20 h; Inert atmosphereGlovebox; Reagent/catalyst; regioselective reaction;
参考文献
Chinnagolla, Ravi Kiran; Jeganmohan, Masilamani
Chemical Communications, 2014 , vol. 50, # 19 p. 2442 - 2444
反应条件
tetrakis(triphenylphosphine) palladium(0); potassium carbonate in water; acetonitrile
T=100°C; Suzuki-Miyaura coupling; Inert atmosphere;
参考文献
Kajiyama, Daichi; Inoue, Keisuke; Ishikawa, Yuichi; Nishiyama, Shigeru
Tetrahedron, 2010 , vol. 66, # 52 p. 9779 - 9784
反应条件
tetrabutylammomium bromide; potassium carbonate; [1-cyclohexyl-3-(di-pyridin-2-yl-methyl)-urea][PdCl2] in water
T=100°C; Suzuki-Miyaura coupling; 47 h;
参考文献
Najera, Carmen; Gil-Molto, Juan; Karlstroem, Sofia
Advanced Synthesis and Catalysis, 2004 , vol. 346, # 13-15 p. 1798 - 1811
反应条件
1: tin; hydrochloric acid
2: 0 °C
View Scheme
参考文献
Scarborough; Waters
Journal of the Chemical Society, 1927 , p. 94
