3-(甲氧羰基)二苯甲酮合成路线 (共 10 条)
反应条件
toluene-4-sulfonic acid T=75°C; 18 h;
参考文献
CHIESI FARMACEUTICI S.p.A.; RANCATI, Fabio; RIZZI, Andrea; AMARI, Gabriele; BIAGETTI, Matteo; LINNEY, Ian
Patent: WO2012/168359 A1, 2012 ;
Location in patent: Page/Page column 135 ;
WO 2012/168359 A1
反应条件
1: 76 percent / benzene; diethyl ether / 1 h / Heating 2: 3.0 g / sodium dichromate, conc. sulfuric acid / acetic acid; H2O; acetic acid / Ambient temperature 3: 1 g / 30percent alcoholic KOH / Heating 4: 0.2 g / sulfuric acid / Heating View Scheme
参考文献
Wagner, Peter J.; Siebert, Elizabeth J.
Journal of the American Chemical Society, 1981 , vol. 103, # 24 p. 7329 - 7335
反应条件
1: 3.0 g / sodium dichromate, conc. sulfuric acid / acetic acid; H2O; acetic acid / Ambient temperature 2: 1 g / 30percent alcoholic KOH / Heating 3: 0.2 g / sulfuric acid / Heating View Scheme
参考文献
Wagner, Peter J.; Siebert, Elizabeth J.
Journal of the American Chemical Society, 1981 , vol. 103, # 24 p. 7329 - 7335
反应条件
1: 1 g / 30percent alcoholic KOH / Heating 2: 0.2 g / sulfuric acid / Heating View Scheme
参考文献
Wagner, Peter J.; Siebert, Elizabeth J.
Journal of the American Chemical Society, 1981 , vol. 103, # 24 p. 7329 - 7335
反应条件
microwave irradiation;
参考文献
Lee, Jong Chan; Song, In-Goul; Park, Jin Young
Synthetic Communications, 2002 , vol. 32, # 14 p. 2209 - 2213
反应条件
aluminium trichloride T=100 - 110°C; Acylation; 0.333333 h; Title compound not separated from byproducts;
参考文献
Belen'kii; Gromova; Kolotaev; Krayushkin
Chemistry of Heterocyclic Compounds, 2000 , vol. 36, # 3 p. 256 - 263
参考文献
Budesinsky, Milos; Exner, Otto
Magnetic Resonance in Chemistry, 1989 , vol. 27, # 6 p. 585 - 591
参考文献
Senff
Justus Liebigs Annalen der Chemie, 1883 , vol. 220, p. 230
反应条件
24 h; Ambient temperature; Yield given;
参考文献
Degani, Iacopo; Dughera, Stefano; Fochi, Rita; Gazzetto, Sonia
Journal of Organic Chemistry, 1997 , vol. 62, # 21 p. 7228 - 7233
反应条件
triethylsilane; sulfuric acid in methanol; trifluoroacetic acid
参考文献
Elworthy, Todd Richard; Mirzadegan, Tara; Roepel, Michael Garret; Smith, David Bernard; Walker, Keith Adrian
Patent: US2003/120079 A1, 2003 ;
US 20030120079 A1