1,3-二噻烷-2-基(苯基)甲酮合成路线 （共 18 条）
反应条件
1: in tetrahydrofuran
T=-30 - -25°C; 2 h; Inert atmosphere;
2: With water; ammonium chloride in tetrahydrofuran
Inert atmosphere;
参考文献
Balasubramaniam, Sivaraman; Kommidi, Harikrishna; Aidhen, Indrapal Singh
Tetrahedron Letters, 2011 , vol. 52, # 21 p. 2683 - 2686
反应条件
diisobutylaluminium hydride in hexane; toluene
T=-78°C; 6.5 h;
参考文献
Trost, Barry M.; Hiroi, Kunio; Jungheim, Louis N.
Journal of Organic Chemistry, 1980 , vol. 45, # 10 p. 1839 - 1847
反应条件
sodium hydride in N,N-dimethyl-formamide
T=0°C; 0.5 h;
参考文献
Rivera, Nancy Gonzalez; Becerril, David Corona; Guadarrama-Perez, Carlos; Covarrubias-Zuniga, Adrian; Avila-Zarraga, Jose Gustavo; Romero-Ortega, Moises
Tetrahedron Letters, 2007 , vol. 48, # 7 p. 1201 - 1204
反应条件
in tetrahydrofuran
T=-20 - 0°C;
参考文献
Wattanasin, S.; Kathawala, F.G.
Tetrahedron Letters, 1984 , vol. 25, # 8 p. 811 - 814
反应条件
n-butyllithium in tetrahydrofuran
-78 deg C, 2 h then rt.;
参考文献
Bulman Page, Philip C.; Marchington, Allan P.; Graham, Lisa J.; Harkin, Shaun A.; Wood, William W.
Tetrahedron, 1993 , vol. 49, # 45 p. 10369 - 10386
反应条件
in tetrahydrofuran
T=0°C; 2 h;
参考文献
Balasubramaniam, Sivaraman; Aidhen, Indrapal Singh
Synlett, 2007 , # 6 p. 959 - 963
反应条件
in tetrahydrofuran
T=0°C;
参考文献
Malanga, Corrado; Aronica, Laura A.; Lardicci, Luciano
Tetrahedron Letters, 1995 , vol. 36, # 50 p. 9185 - 9188
反应条件
1: 69 percent / Pb(OAc)4 / benzene / 12 h / 55 °C
2: 40 percent / KOH / tetrahydrofuran; H2O / 10 h / 0 °C
View Scheme
参考文献
Hiroi; Sato; Matsuo
Chemical and Pharmaceutical Bulletin, 1980 , vol. 28, # 2 p. 558 - 566
反应条件
in tetrahydrofuran; hexane
-78 deg C to room t.;
参考文献
Page, Philip C. Bulman; van Niel, Monique B.; Westwood, Donald
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1988 , p. 269 - 276
反应条件
1: triethylamine / petroleum ether / 0.75 h / 0 °C
2: 73 percent / tetrahydrofuran / -20 - 0 °C
View Scheme
参考文献
Wattanasin, S.; Kathawala, F.G.
Tetrahedron Letters, 1984 , vol. 25, # 8 p. 811 - 814
