3-甲基-2-苯并恶唑酮合成路线 （共 63 条）
反应条件
1: NaOH / H2O / 1 h / Heating
2: acetic acid / 0.5 h / Heating
View Scheme
参考文献
Anderson; Bell
Journal of the Chemical Society, 1949 , p. 2668,2670
反应条件
1: ClSO3H / 3 h
2: NH3 / ethanol / 2 h / Heating
View Scheme
参考文献
Savitskaya,N.V. et al.
Pharmaceutical Chemistry Journal, 1976 , vol. 10, # 7 p. 868 - 872
Khimiko-Farmatsevticheskii Zhurnal, 1976 , vol. 10, # 7 p. 23 - 28
反应条件
1: ClSO3H / 3 h
2: benzene / 3.5 h / Heating
View Scheme
参考文献
Karimova; Dushamov; Kuryazov; Mukhamedov
Chemistry of Heterocyclic Compounds, 2011 , vol. 47, # 1 p. 90 - 95
参考文献
Moussavi; Depreux; Lesieur; Cotelle; Sauzieres; Plancke; Fruchart
Farmaco, 1991 , vol. 46, # 2 p. 339 - 355
反应条件
aluminium trichloride in N,N-dimethyl-formamide
Acylation; Friedel-Crafts reaction; 4.5 h; Heating;
参考文献
Liacha, Messaoud; Yous, Said; Poupaert, Jacques H.; Depreux, Patrick; Aichaoui, Hocine
Monatshefte fur Chemie, 1999 , vol. 130, # 11 p. 1393 - 1397
反应条件
aluminium trichloride in N,N-dimethyl-formamide
T=75°C; 2 h;
参考文献
Aichaoui, Hocine; Lesieur, Daniel; Henichart, Jean-Pierre
Journal of Heterocyclic Chemistry, 1992 , vol. 29, # 1 p. 171 - 175
参考文献
Moussavi, Ziaeddine; Lesieur, Daniel; Lespagnol, Charles; Sauzieres, Jacques; Olivier, Philippe
European Journal of Medicinal Chemistry, 1989 , vol. 24, p. 55 - 60
反应条件
1: 70 percent / polyphosphoric acid
2: 85 percent / NaOH
View Scheme
参考文献
Moussavi, Ziaeddine; Lesieur, Daniel; Lespagnol, Charles; Sauzieres, Jacques; Olivier, Philippe
European Journal of Medicinal Chemistry, 1989 , vol. 24, p. 55 - 60
反应条件
1: 68 percent / trifluoroacetic acid / 20 h / Heating
2: aq. NaOH / 4 h / Heating
View Scheme
参考文献
Petrov, Ognyan I.; Kalcheva, Veneta B.; Antonova, Antonina Ts.
Collection of Czechoslovak Chemical Communications, 1997 , vol. 62, # 3 p. 494 - 497
反应条件
polyphosphoric acid
T=90°C; Friedel Crafts acylation; 0.366667 h; Microwave irradiation;
参考文献
Baytas, Sultan; Turan Dural, Niludie Nermin; Oezkan, Yesim; Simsek, Hasan Bolkan; Guersel, Tuerkiz; Uenlue, Serdar
Turkish Journal of Chemistry, 2012 , vol. 36, # 3 p. 367 - 382
