6,7-二氢-5H-异喹啉-8-酮合成路线 (共 5 条)
反应条件
chromium(VI) oxide; sulfuric acid; acetic acid in water T=15 - 20°C; 5 h;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 1 p. 31 - 35
反应条件
tert.-butylhydroperoxide; potassium iodide in water; acetonitrile T=20°C; 24 h;
参考文献
Kumar, R. Arun; Maheswari, C. Uma; Ghantasala, Satheesh; Jyothi; Reddy, K. Rajender
Advanced Synthesis and Catalysis, 2011 , vol. 353, # 2-3 p. 401 - 410
反应条件
hydrogenchloride 24 h; Heating;
参考文献
Glassco; Suchocki; George; Martin; May
Journal of Medicinal Chemistry, 1993 , vol. 36, # 22 p. 3381 - 3385
参考文献
Yakugaku Zasshi, , vol. 76, p. 1308
Chem.Abstr., , p. 5076
反应条件
1: 89 percent / NaBH4 / methanol / 1) 0 deg C, 1 h, 2) rt, overnight
2: 88 percent / polyphosphoric acid / 0.67 h / 90 °C
View Scheme
参考文献
Boyd, Derek R.; Davies, R. Jeremy H.; Hamilton, Lynne; McCullough, John J.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1992 , # 1 p. 31 - 35