2,3,4,5,6,7-六氢-1H-茚-1-酮合成路线 （共 57 条）
反应条件
pyridine; tetrabutyl-ammonium chloride; bis(dibenzylideneacetone)-palladium(0) in N,N-dimethyl-formamide
T=100°C; P=760 Torr; 72 h;
参考文献
Gagnier, Steve V.; Larock, Richard C.
Journal of the American Chemical Society, 2003 , vol. 125, # 16 p. 4804 - 4807
反应条件
pyridine; palladium diacetate; tetrabutyl-ammonium chloride in N,N-dimethyl-formamide
T=100°C; P=760 Torr; 72 h;
参考文献
Gagnier, Steve V.; Larock, Richard C.
Journal of the American Chemical Society, 2003 , vol. 125, # 16 p. 4804 - 4807
反应条件
pyridine; palladium diacetate; tetrabutyl-ammonium chloride in N,N-dimethyl-formamide
T=100°C; P=760 Torr; 12 h;
参考文献
Gagnier, Steve V.; Larock, Richard C.
Journal of the American Chemical Society, 2003 , vol. 125, # 16 p. 4804 - 4807
反应条件
trans-4-fluoro-L-proline in dimethyl sulfoxide
T=20°C; 24 h;
参考文献
Chandler, Carley L.; List, Benjamin
Journal of the American Chemical Society, 2008 , vol. 130, # 21 p. 6737 - 6739
反应条件
methanesulfonic acid; phosphorus pentoxide
Ambient temperature;
参考文献
Murthy; Pillai
Tetrahedron, 1992 , vol. 48, # 25 p. 5331 - 5346
反应条件
TpRuPPh3(MeCN)2SbF6 in toluene
T=105°C; 20 h;
参考文献
Odedra, Arjan; Datta, Swarup; Liu, Rai-Shung
Journal of Organic Chemistry, 2007 , vol. 72, # 9 p. 3289 - 3292
反应条件
toluene-4-sulfonic acid in benzene
0.166667 h; Heating;
参考文献
Shono, Tatsuya; Kise, Naoki; Fujimoto, Taku; Tominaga, Naoto; Morita, Hiroshi
Journal of Organic Chemistry, 1992 , vol. 57, # 28 p. 7175 - 7187
反应条件
1: 85 percent / CuI; diethylamine / Pd(PPh3)2Cl2 / toluene / 12 h / 28 °C
2: 82 percent / NaBH4 / methanol / 0.5 h / 0 °C
3: 89 percent / imidazole / dimethylformamide / 5 h / 0 °C
4: 93 percent / K2CO3; MeOH / CH2Cl2 / 25 °C
5: 63 percent / TpRuPPh3(MeCN)2SbF6 / toluene / 20 h / 105 °C
View Scheme
参考文献
Odedra, Arjan; Datta, Swarup; Liu, Rai-Shung
Journal of Organic Chemistry, 2007 , vol. 72, # 9 p. 3289 - 3292
反应条件
1.1: PBr3 / CHCl3 / 1 h / 0 °C
1.2: 30 percent / CHCl3 / 1 h / Heating
2.1: n-BuLi / tetrahydrofuran / 0.5 h / 0 °C
2.2: 82 percent / tetrahydrofuran / 1 h
3.1: 87 percent / Pd(dba)2; pyridine; n-Bu4NCl / dimethylformamide / 72 h / 100 °C / 760 Torr
View Scheme
参考文献
Gagnier, Steve V.; Larock, Richard C.
Journal of the American Chemical Society, 2003 , vol. 125, # 16 p. 4804 - 4807
反应条件
1.1: Mg; MeI / tetrahydrofuran / 2 h / Heating
1.2: I2 / tetrahydrofuran / 1 h / 20 °C
2.1: 86 percent / Pd(OAc)2; pyridine; n-Bu4NCl / dimethylformamide / 72 h / 100 °C / 760 Torr
View Scheme
参考文献
Gagnier, Steve V.; Larock, Richard C.
Journal of the American Chemical Society, 2003 , vol. 125, # 16 p. 4804 - 4807
