2-氨基-5-硝基-6-甲基吡啶合成路线 （共 28 条）
反应条件
sulfuric acid in water
参考文献
Bristol-Myers Squibb Company
Patent: US6011029 A1, 2000 ;
反应条件
hydrogenchloride; sodium nitrite Diazotization;
参考文献
Parker; Shive
Journal of the American Chemical Society, 1947 , vol. 69, p. 63,66
反应条件
1: hydrogenchloride; sodium nitrite 2: phosphorus pentachloride; trichlorophosphate 3: palladium on carbon; hydrogen 4: tetrafluoroboric acid; EtO-NO 5: iodine; potassium acetate / acetic anhydride 6: ozone View Scheme
参考文献
Timperley, Christopher M.; Banks, R. Eric; Young, Ian M.; Haszeldine, Robert N.
Journal of Fluorine Chemistry, 2011 , vol. 132, # 8 p. 541 - 547
反应条件
palladium in ethanol
参考文献
ALLERGAN, INC.; HEIDELBAUGH, Todd M.; CAPPIELLO, John R.; NGUYEN, Phong; GOMEZ, Dario G.
Patent: WO2011/50054 A2, 2011 ;
Location in patent: Page/Page column 49 ;
WO 2011/050054 A1
反应条件
1: aqueous sodium nitrite; aqueous sulfuric acid / Diazotization 2: phosphorus (V)-chloride; phosphoryl chloride 3: methanol View Scheme
参考文献
MERCK and CO., INC.
Patent: WO2009/155156 A1, 2009 ;
WO 2009/155156 A1
反应条件
hydrazine in water T=110 - 120°C; 5 h;
参考文献
Smolyar; Yutilov
Russian Journal of Organic Chemistry, 2009 , vol. 45, # 1 p. 115 - 118
反应条件
1: aqueous sodium nitrite; aqueous sulfuric acid / Diazotization 2: phosphorus (V)-chloride; phosphoryl chloride View Scheme
参考文献
Timperley, Christopher M.; Banks, R. Eric; Young, Ian M.; Haszeldine, Robert N.
Journal of Fluorine Chemistry, 2011 , vol. 132, # 8 p. 541 - 547
反应条件
hydrogenchloride; sodium nitrite Diazotization;
参考文献
Parker; Shive
Journal of the American Chemical Society, 1947 , vol. 69, p. 63,66
反应条件
bromine; acetic acid
参考文献
Parker; Shive
Journal of the American Chemical Society, 1947 , vol. 69, p. 63,66
参考文献
Parker; Shive
Journal of the American Chemical Society, 1947 , vol. 69, p. 63,66
