(S)-(+)-1,2-异亚丙基甘油合成路线 （共 82 条）
反应条件
pig liver esterase; water; methoxypolyethylene glycol in toluene T=20°C; Acylation; kinetic resolution; 120 h; Title compound not separated from byproducts;
参考文献
Tetrahedron Asymmetry, , vol. 10, # 19 p. 3747 - 3758
反应条件
recombinant Escherichia coli esterase YbfF W235I mutant in aq. buffer T=30°C; pH=7.5; Enzymatic reaction; Kinetics; ConcentrationReagent/catalyst;
参考文献
Advanced Synthesis and Catalysis, , vol. 354, # 16 p. 3009 - 3015
反应条件
immobilized penicillinacylase from E. coli in water; acetonitrile Ambient temperaturestopped at 50percent conversion;
参考文献
Tetrahedron, , vol. 44, # 9 p. 2575 - 2582
反应条件
Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Tetrahedron, , vol. 48, # 6 p. 1071 - 1080
参考文献
Tetrahedron Letters, , vol. 34, # 25 p. 4047 - 4050
参考文献
Tetrahedron Asymmetry, , vol. 8, # 6 p. 923 - 933
反应条件
1: octadecanyl bromide With sodium hydride in tetrahydrofuran T=0°C; 1 h; 2: (S)-(+)-(2,2-Dimethyl-[1,3]dioxolan-4-yl)-methanol in tetrahydrofuran T=0 - 20°C; 10 h;
参考文献
ALIOS BIOPHARMA, INC.; Beigelman, Leonid; Wang, Guangyi; Smith, David Bernard; Deval, Jerome; Prhavc, Marija
Patent: US2013/165400 A1, 2013 ;
Location in patent: Paragraph 0782; 0783 ;
反应条件
sodium hydride in N,N-dimethyl-formamide; Petroleum ether T=50°C; 3 h;
参考文献
Hirth; Barner
Helvetica Chimica Acta, 1982 , vol. 65, # 3 p. 1059 - 1084
参考文献
Baer; Fischer
Journal of Biological Chemistry, 1941 , vol. 140, p. 397,406
参考文献
Takano; Akiyama; Ogasawara
Chemical and Pharmaceutical Bulletin, 1984 , vol. 32, # 2 p. 791 - 794
