乙酸4-（二乙氨基）-2-丁炔醇酯合成路线 （共 10 条）
反应条件
1: With sulfuric acid T=65 - 70°C; 2 h; 2: With sodium hydrogencarbonate in dichloromethane; water Saturated solution;
参考文献
MATRIX LABORATORIES LIMITED
Patent: WO2009/122429 A2, 2009 ;
Location in patent: Page/Page column 6 ;
反应条件
Cu2Cl2; acetic acid in 1,4-dioxane T=0°C; Heating / reflux;
参考文献
SALAMA, Zoser, B.
Patent: WO2005/95369 A1, 2005 ;
Location in patent: Page/Page column 47; 48 ;
参考文献
Journal of the American Pharmaceutical Association, Scientific Edition, , vol. 49, p. 112 - 114
参考文献
Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, , vol. 226, p. 1289
反应条件
sodium methylate in n-heptane T=65 - 100°C; Inert atmosphere;
参考文献
MATRIX LABORATORIES LIMITED
Patent: WO2009/122429 A2, 2009 ;
Location in patent: Page/Page column 6-7 ;
反应条件
nickel Hydrogenation;
参考文献
Marszak; Marszak-Fleury
Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1948 , vol. 226, p. 1289
参考文献
Marszak; Marszak-Fleury
Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1948 , vol. 226, p. 1289
反应条件
sodium methylate in n-heptane T=65 - 100°C; Inert atmosphere;
参考文献
MATRIX LABORATORIES LIMITED
Patent: WO2009/122429 A2, 2009 ;
Location in patent: Page/Page column 6-7 ;
反应条件
sodium methylate in n-heptane T=65 - 100°C; Inert atmosphere;
参考文献
MATRIX LABORATORIES LIMITED
Patent: WO2009/122429 A2, 2009 ;
Location in patent: Page/Page column 6-7 ;
反应条件
sodium methylate in n-heptane T=65 - 100°C; Inert atmosphere;
参考文献
MATRIX LABORATORIES LIMITED
Patent: WO2009/122429 A2, 2009 ;
Location in patent: Page/Page column 6-7 ;
