4-(4-硝基苯氧基)苯酚合成路线 (共 20 条)
反应条件
hydrogen bromide; acetic acid 16 h; Inert atmosphereSchlenk techniqueReflux;
参考文献
Bao, Xiaofeng; Jin, Yanyan; Liu, Xiaolu; Liao, Hong; Zhang, Luyong; Pang, Tao
RSC Advances, 2014 , vol. 4, # 13 p. 6761 - 6775
反应条件
potassium carbonate in N,N-dimethyl-formamide Heating;
参考文献
Yamada, Ayumi; Fujii, Shinya; Mori, Shuichi; Kagechika, Hiroyuki
ACS Medicinal Chemistry Letters, 2013 , vol. 4, # 10 p. 937 - 941
反应条件
potassium hydroxide in dimethyl sulfoxide 16 h; Heating;
参考文献
Vangala, Venu R.; Bhogala, Balakrishna R.; Dey, Archan; Desiraju, Gautam R.; Broder, Charlotte K.; Smith, Philip S.; Mondal, Raju; Howard, Judith A. K.; Wilson, Chick C.
Journal of the American Chemical Society, 2003 , vol. 125, # 47 p. 14495 - 14509
反应条件
sodium hydroxide in ethanol; water 20 h; Heating / reflux;
参考文献
BAYER CORPORATION
Patent: US2004/2508 A1, 2004 ;
Location in patent: Page/Page column 16 ;
US 20040002508 A1
反应条件
potassium hydroxide; hydroquinone in (2S)-N-methyl-1-phenylpropan-2-amine hydrate; dimethyl sulfoxide
参考文献
Ciba-Geigy Corporation
Patent: US4214086 A1, 1980 ;
反应条件
sodium hydroxide in dimethyl sulfoxide T=50°C; 5 h;
参考文献
Xie, Chaoyu; Sullivan, Kevin A.; Laurila, Michael E.; Mitchell, David N.; Pu, Y. John
Synthetic Communications, 2008 , vol. 38, # 1 p. 21 - 32
反应条件
potassium hydroxide in dimethyl sulfoxide T=20°C; 16 h;
参考文献
Dey, Archan; Desiraju, Gautam R.
Chemical Communications, 2005 , # 19 p. 2486 - 2488
反应条件
1: Cu 2: AlCl3 / nitrobenzene View Scheme
参考文献
Steller,K.E.; Letsinger,R.L.
Journal of Organic Chemistry, 1970 , vol. 35, p. 308 - 313
反应条件
1: Cu 2: AlCl3 / nitrobenzene View Scheme
参考文献
Steller,K.E.; Letsinger,R.L.
Journal of Organic Chemistry, 1970 , vol. 35, p. 308 - 313
反应条件
1.1: potassium hydroxide / 0.17 h / 150 °C 1.2: 2 h / 170 °C 2.1: boron tribromide / dichloromethane / 3 h / 0 - 20 °C View Scheme
参考文献
Cinque, Gueendalina M.; Szajnman, Sergio H.; Zhong, Li; Docampo, Roberto; Schvartzapel, Andrea J.; Rodriguez, Juan B.; Gros, Eduardo G.
Journal of Medicinal Chemistry, 1998 , vol. 41, # 9 p. 1540 - 1554