2H-苯并吡喃-3-甲酸合成路线 (共 29 条)
反应条件
1: With sodium hydroxide; water T=100°C; 2 h; Heating / reflux; 2: With hydrogenchloride in water T=0 - 5°C; pH=1;
参考文献
PIERRE FABRE MEDICAMENT
Patent: WO2008/9741 A1, 2008 ;
Location in patent: Page/Page column 24-25 ;
WO 2008/009741 A1
反应条件
1,4-diaza-bicyclo[2.2.2]octane in water T=20°C; 2 h;
参考文献
Ravichandran
Synthetic Communications, 2001 , vol. 31, # 8 p. 1233 - 1235
反应条件
triethylamine in sodium hydroxide; toluene
反应条件
trifluoroacetic acid Ambient temperature;
参考文献
Satoh; Stanton; Hutchison; Libby; Kowalski; Lee; White; Kimble
Journal of Medicinal Chemistry, 1993 , vol. 36, # 23 p. 3580 - 3594
反应条件
1: 16 percent / 20percent aq.NaOH 2: 94.7 percent / 10percent NaOH / 5 h / Heating View Scheme
参考文献
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 21, # 4 p. 344 - 347
反应条件
sodium hydroxide 5 h; Heating;
参考文献
Gupta, R. C.; Pratap, Ram; Prasad, C. R.; Anand, Nitya
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1982 , vol. 21, # 4 p. 344 - 347
参考文献
Journal of the Chemical Society, , p. 2724
反应条件
hydrogenchloride in methanol
参考文献
Cheng, Xue-Min; Filzen, Gary F.; Geyer, Andrew G.; Lee, Chitase; Trivedi, Bharat K.
Patent: US2003/207915 A1, 2003 ;
US 20030207915 A1