2-甲氧基-2-甲基-1-丙醇合成路线 （共 12 条）
反应条件
1: With sulfuric acid 4 h; Heating / reflux; 2: With potassium hydroxide in methanol T=20°C; pH=7;
参考文献
DRAXIS Specialty Pharmaceuticals Inc.
Patent: US2008/102028 A1, 2008 ;
Location in patent: Page/Page column 9; 10 ;
参考文献
Merck Frosst Canada and Co.
Patent: US6046217 A1, 2000 ;
反应条件
H(+)-zeolite-X in benzene T=25°C; 0.5 h;
参考文献
Takeuchi, Hiroshi; Kishioka, Hiroaki; Kitajima, Kunio
Journal of Physical Organic Chemistry, 1995 , vol. 8, # 2 p. 121 - 126
反应条件
lithium aluminium tetrahydride
参考文献
Leggetter,B.E.; Brown,R.K.
Canadian Journal of Chemistry, 1964 , vol. 42, p. 990 - 1004
反应条件
dihydrogen peroxide; aluminium titanium silicate Al-TS-1 T=100°C; 4 h; other temperature, reaction; Product distribution;
参考文献
Van Grieken; Ovejero; Serrano; Uguina; Melero
Chemical Communications, 1996 , # 10 p. 1145 - 1146
参考文献
Sparks; Nelson
Journal of the American Chemical Society, 1936 , vol. 58, p. 671
参考文献
Petrow; Pritula
Zhurnal Prikladnoi Khimii (Sankt-Peterburg, Russian Federation), 1955 , vol. 28, p. 556,558
Chem.Abstr., 1956 , p. 4003
反应条件
di-isopropyl azodicarboxylate; triphenylphosphine in tetrahydrofuran 3 h; Product distribution / selectivity;
参考文献
DRAXIS Specialty Pharmaceuticals Inc.
Patent: US2008/102028 A1, 2008 ;
Location in patent: Page/Page column 9; 10-11 ;
反应条件
perchloric acid T=0°C; 6 h;
参考文献
Wang, Zhi-Xian; Tu, Yong; Frohn, Michael; Zhang, Jian-Rong; Shi, Yian
Journal of the American Chemical Society, 1997 , vol. 119, # 46 p. 11224 - 11235
反应条件
oxalyl dichloride; dimethyl sulfoxide in dichloromethane T=-70°C; 0.25 h; Inert atmosphere;
参考文献
BAYER PHARMA AKTIENGESELLSCHAFT; HAHN, Michael; LAMPE, Thomas; STASCH, Johannes-Peter; SCHLEMMER, Karl-Heinz; WUNDER, Frank; LI, Volkhart Min-Jian; BECKER, Eva-Maria; STOLL, Friederike; KNORR, Andreas; WOLTERING, Elisabeth
Patent: US2013/79412 A1, 2013 ;
Location in patent: Paragraph 0353-0355 ;
