5-溴-2-甲基-2-戊烯合成路线 （共 93 条）
反应条件
1: ethanol 2: KOH / ethanol 3: H2 / Pt / ethanol View Scheme
参考文献
Julia,S. et al.
Bulletin de la Societe Chimique de France, 1962 , p. 1952 - 1959
反应条件
n-butyllithium 1.) ether, -72 deg C, 2.) 48 h;
参考文献
Elvidge, John A.; Jones, Stephen P.; Peppard, Terence L.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1982 , p. 1089 - 1094
反应条件
(i) Li, Et2O, (ii) /BRN= 1209258/; Multistep reaction;
参考文献
Parker,K.A.; Johnson,W.S.
Journal of the American Chemical Society, 1974 , vol. 96, p. 2556 - 2563
反应条件
NaCN in dimethylformamide [DMF]
参考文献
Bracco International B.V.
Patent: US5688487 A1, 1997 ;
反应条件
in dimethyl sulfoxide Ambient temperature;
参考文献
Mori, Kenji; Sugai, Takeshi; Maeda, Yukari; Okazaki, Tomomi; Noguchi, Tadashi; Naito, Hiroshi
Tetrahedron, 1985 , vol. 41, # 22 p. 5307 - 5312
反应条件
sodium methylate in methanol
参考文献
Ershov,B.A. et al.
Journal of Organic Chemistry USSR (English Translation), 1968 , vol. 4, p. 776 - 779
Zhurnal Organicheskoi Khimii, 1968 , vol. 4, p. 796 - 801
反应条件
1: alkali metal iodide 2: t-BuLi / pentane; tetrahydrofuran / -30 - 20 °C 3: NiCl2(PPh3)2 / diethyl ether; benzene / 0.67 h / Heating 4: pyridine / CH2Cl2 / 0 - 20 °C 5: 2.1 g / NaI / acetone / 3 h / 50 °C View Scheme
参考文献
Blanc, Aurelien; Toste, F. Dean
Angewandte Chemie - International Edition, 2006 , vol. 45, # 13 p. 2096 - 2099
反应条件
potassium carbonate in dimethyl sulfoxide T=20°C;
参考文献
Ishizuka, Kentaro; Seike, Hirofumi; Hatakeyama, Takuji; Nakamura, Masaharu
Journal of the American Chemical Society, 2010 , vol. 132, # 38 p. 13117 - 13119
参考文献
Clennan, Edward L.; Zhou, Wenhui; Chan, Jacqueline
Journal of Organic Chemistry, 2002 , vol. 67, # 26 p. 9368 - 9378
反应条件
1: 1.) sodium ethoxide / 1.) ethanol, 50 deg C, 1 h, 2.) reflux, 3 h 2: 90 percent / NaOH / methanol / 2 h / Heating 3: 96 percent / water, pyridine / 5 h / Heating View Scheme
参考文献
Julia,S. et al.
Bulletin de la Societe Chimique de France, 1962 , p. 1952 - 1959
