反应条件
3: 99 percent / DMSO, (COCl)2, Et3N / CH2Cl2 4: 96 percent / PPh3 / benzene / 80 °C 5: 84 percent / n-BuLi / tetrahydrofuran / -78 °C 6: 1.) n-BuLi / 1.) THF, -78 deg C, 2.) oxidation 7: 1.) camphorsulfonic acid, 2.) n-Bu4NF / 1.) room temperature, 2.) dioxane-THF, 65 deg C 8: 88 percent / H2 / Lindlar / methanol 9: 1.) DMSO,(COCl)2, Et3N, 2.) CSA / 1.) CH2Cl2, 2.) CH2Cl2, room temperature 10: (C6H11)2NMgBr / methanol / -55 °C 11: DDQ / CH2Cl2 / 1.5 h / Ambient temperature; buffer (pH 6.86) View Scheme
参考文献
Horita; Oikawa; Nagato; Yonemitsu
Tetrahedron Letters, 1988 , vol. 29, # 40 p. 5143 - 5146
