反应条件
1: 1) NaH / 1) THF, r.t., 30 min, 2) THF, DMF, r.t., 90 min
2: 60 percent / NaBH4, CF3COOH / tetrahydrofuran / 20 h / ice bath cooling up to reflux
3: 1) CF3COOH, 2) 2-ethoxyethyl ether / 2) 10 percent Pd/C / 1) r.t., 30 min, 2) reflux, 6 h
4: 1) 32 percent peracetic acid, 2) aq. conc. HCl / 1) THF, 0 deg C, 20 min, 2) MeOH, 1 h
View Scheme
参考文献
Pelcman; Gribble
Tetrahedron Letters, 1990 , vol. 31, # 17 p. 2381 - 2384
