N-CBZ-beta-丙氨酸合成路线 （共 48 条）
反应条件
sodium hydroxide in water T=0 - 20°C;
参考文献
Schmuck, Carsten; Rehm, Thomas; Geiger, Lars; Schaefer, Mathias
Journal of Organic Chemistry, 2007 , vol. 72, # 16 p. 6162 - 6170
反应条件
hydrogenchloride in sodium hydroxide; toluene
反应条件
silver trifluoroacetate in 1,4-dioxane; water Wolff rearrangement; 0.5 h; sonication;
参考文献
Helvetica Chimica Acta, , vol. 89, # 11 p. 2611 - 2637
反应条件
1.1: ClCOOEt; N-methylmorpholine / tetrahydrofuran / 0.25 h / -15 °C 1.2: tetrahydrofuran; CH2Cl2 / -15 - 20 °C 2.1: CF3COOAg / dioxane; H2O / 0.5 h / sonication View Scheme
参考文献
Helvetica Chimica Acta, , vol. 89, # 11 p. 2611 - 2637
反应条件
trifluoroacetic acid 0.5 h;
参考文献
Chemical Communications, , # 21 p. 2554 - 2555
反应条件
1: Et3N / 0.17 h / 20 °C 2: CF3CO2H / 0.5 h View Scheme
参考文献
Chemical Communications, , # 21 p. 2554 - 2555
反应条件
sodium hydroxide in methanol 1 h;
参考文献
Amino Acids, , vol. 44, # 3 p. 1085 - 1091
参考文献
Monatshefte fuer Chemie, , vol. 89, p. 61,66,70
反应条件
1: pyridine 2: aq.-ethanolic NaOH View Scheme
参考文献
Monatshefte fuer Chemie, , vol. 89, p. 61,66,70
反应条件
1H-imidazole; water in ethanol T=25°C; phosphate buffer (pH=8.05); MechanismKinetics;
参考文献
Journal of Organic Chemistry USSR (English Translation), , vol. 18, p. 1712 - 1715
Zhurnal Organicheskoi Khimii, , vol. 18, # 9 p. 1954 - 1958
