N-苄氧羰基-L-天冬酰胺合成路线 (共 51 条)
反应条件
n-ethyl morpholine; benzotriazol-1-ol in N,N-dimethyl-formamide 1) 2 h, -20 deg C, 2) 6 h, 0 deg C; overnight, r.t.;
参考文献
Appel, Rolf; Glaesel, Ursula; Glaesel, Volker Ingo
Chemische Berichte, 1981 , vol. 114, # 4 p. 1542 - 1545
反应条件
1: DCC / dimethylformamide 2: Et3N / CHCl3; dimethylformamide View Scheme
参考文献
Miroshnikov,A.I. et al.
J. Gen. Chem. USSR (Engl. Transl.), 1970 , vol. 40, # 1 p. 223 - 235,202 - 213
反应条件
benzotriazol-1-ol; dicyclohexyl-carbodiimide
参考文献
Koenig,W.; Geiger,R.
Chemische Berichte, 1970 , vol. 103, p. 788 - 798
反应条件
sodium hydroxide; chlorine
参考文献
Recueil des Travaux Chimiques des Pays-Bas, , vol. 83, p. 1078 - 1082
反应条件
tetrahydrofuran; N,N-dimethyl-formamide; dicyclohexyl-carbodiimide
参考文献
Katsoyannis et al.
Journal of the American Chemical Society, 1958 , vol. 80, p. 2558,2560
反应条件
tetrahydrofuran; triethylamine; 3-methyl-butyryl chloride Reagens 4: THF;;
参考文献
Zaoral,M.
Collection of Czechoslovak Chemical Communications, 1962 , vol. 27, p. 1273 - 1277
反应条件
1: dicyclohexylcarbodiimide; DMF 2: triethylamine; DMF View Scheme
参考文献
Bodanszky; du Vigneaud
Journal of the American Chemical Society, 1959 , vol. 81, p. 5688,5689, 5690
Biochemical Preparations, 1962 , vol. 9, p. 110,111 Anm. 2
反应条件
pyridine; toluene; phosphorus trichoride
参考文献
Boissonnas et al.
Helvetica Chimica Acta, 1955 , vol. 38, p. 1491,1499
参考文献
Galpin; Hancock; Kenner
Tetrahedron, 1983 , vol. 39, # 1 p. 149 - 158
反应条件
trifluoroacetic acid
参考文献
Maurs, Michele; Acher, Francine; Azerad, Robert
Journal of Molecular Catalysis B: Enzymatic, 2012 , vol. 84, p. 22 - 26