1: cycloheptanone With n-butyllithium; diisopropylamine in tetrahydrofuran; hexane
T=-78°C;
2: With titanium(IV) isopropylate in tetrahydrofuran; hexane
T=-78°C;
3: perfluoromethyl iodide With triethyl borane in tetrahydrofuran; hexane
T=-78°C;
pyridine; copper
T=110 - 120°C; 20 h; Title compound not separated from byproducts;
参考文献
Kobayashi, Yoshiro; Kumadaki, Itsumaro
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 661 - 664