3,6,6-三甲基-2-环己烯-1-酮合成路线 （共 32 条）
反应条件
1: 1.) lithium 4,4'-di-tert-butylbiphenylide, 2.) CuBr*Me2S / 1.) THF, 30 min, 2.) THF, -78 deg C, 3 h, 3.) THF, -78 deg C, 12 h
2: 1.) p-toluenesulfonic acid, 2.) 5percent KOH, 40percent n-Bu4NOH / 1.) acetone, water, reflux 7 h, 2.) THF, water, reflux, 14 h
View Scheme
参考文献
Cohen, Theodore; Zhang, Birong; Cherkauskas, John P.
Tetrahedron, 1994 , vol. 50, # 40 p. 11569 - 11584
反应条件
potassium hydroxide; tetra(n-butyl)ammonium hydroxide; toluene-4-sulfonic acid
1.) acetone, water, reflux 7 h, 2.) THF, water, reflux, 14 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Cohen, Theodore; Zhang, Birong; Cherkauskas, John P.
Tetrahedron, 1994 , vol. 50, # 40 p. 11569 - 11584
反应条件
1: concentrated sulfuric acid
2: zinc dust; acetic acid; PtCl4
View Scheme
参考文献
Auwers; Hessenland
Chemische Berichte, 1908 , vol. 41, p. 1815
反应条件
platinum (IV)-chloride; acetic acid; zinc
参考文献
Auwers; Hessenland
Chemische Berichte, 1908 , vol. 41, p. 1815
参考文献
Auwers; Hessenland
Chemische Berichte, 1908 , vol. 41, p. 1815
反应条件
hydrogenchloride; ethanol; lithium diisopropyl amide
Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Takabe, Kunihiko; Ohkawa, Suguru; Katagiri, Takao
Chemistry Letters, 1981 , p. 489 - 490
反应条件
(i), (ii) Py*HClCrO3; Multistep reaction;
参考文献
Dauben,W.G.; Michno,D.M.
Journal of Organic Chemistry, 1977 , vol. 42, # 4 p. 682 - 685
反应条件
Erhitzen d. von <1.2t-Dihydroxy-2c.3.3-trimethyl-cyclopentyl-(r)>-essigsaeure befreiten sauren Anteile d. Reaktionsprod. m. Wasserdampf;
参考文献
Buchman; Sargent
Journal of Organic Chemistry, 1942 , vol. 7, p. 140,145
参考文献
Auwers; Hessenland
Chemische Berichte, 1908 , vol. 41, p. 1815
参考文献
Auwers; Hessenland
Chemische Berichte, 1908 , vol. 41, p. 1815
