hydrogen; rhodium(I)-bis(1,5-cyclooctadiene) tetrafluoroborate; (Sa)-monophos in dichloromethane T=20°C; P=11251.1 Torr; 20 h;

bis(1,5-cyclooctadiene)-rhodium(I) tetrafluoroborate; (R)-1-(3,5-dioxa-4-phosphacyclohepta[2,1-a:3,4-a']dinaphthalen-4-yl)-4-pentafluorophenylmethylpiperazine; hydrogen in ethyl acetate T=20°C; P=15001.5 Torr; 4 h; Inert atmosphereSchlenk technique; Reagent/catalystSolvent; enantioselective reaction;

1: acetic acid; iron; chloro-trimethyl-silane / toluene / 3 h / 70 °C / |Inert atmosphere; |Schlenk technique 2: (R)-1-(3,5-dioxa-4-phosphacyclohepta[2,1-a:3,4-a']dinaphthalen-4-yl)-4-pentafluorophenylmethylpiperazine; bis(1,5-cyclooctadiene)-rhodium(I) tetrafluoroborate; hydrogen / ethyl acetate / 4 h / 20 °C / 15001.5 Torr / |Inert atmosphere; |Schlenk technique View Scheme

1: sodium acetate; hydroxylamine hydrochloride / methanol / 17.5 h / 20 °C / |Inert atmosphere; |Schlenk technique 2: acetic acid; iron; chloro-trimethyl-silane / toluene / 3 h / 70 °C / |Inert atmosphere; |Schlenk technique 3: (R)-1-(3,5-dioxa-4-phosphacyclohepta[2,1-a:3,4-a']dinaphthalen-4-yl)-4-pentafluorophenylmethylpiperazine; bis(1,5-cyclooctadiene)-rhodium(I) tetrafluoroborate; hydrogen / ethyl acetate / 4 h / 20 °C / 15001.5 Torr / |Inert atmosphere; |Schlenk technique View Scheme

暂无反应条件数据

T=-5°C;

暂无反应条件数据

1: N-(1-phenylethyl)acetamide With triphenyl phosphite; chlorine; triethylamine in dichloromethane T=-30°C; 2: ethylene glycol in dichloromethane T=-30 - 20°C; 3: With water

1: N-(1-phenylethyl)acetamide With triphenyl phosphite; chlorine; triethylamine in dichloromethane T=-30°C; 2: ethylene glycol in dichloromethane T=-30 - 20°C; 3: With water

phosphoric acid T=230 - 240°C;