1,5-戊二醇双(对甲苯磺酸)酯合成路线 （共 9 条）
反应条件
in pyridine T=0°C; 5 h;
参考文献
Bush,D.H.; Olszanski,D.J.; Stevens,J.C.
Journal of the American Chemical Society, 1981 , vol. 103, p. 1472
反应条件
potassium iodide; silver(l) oxide in dichloromethane T=20°C; 4 h;
参考文献
Bouzide, Abderrahim; Sauve, Gilles
Organic Letters, 2002 , vol. 4, # 14 p. 2329 - 2332
反应条件
pyridine in dichloromethane
参考文献
Galante, Eva; Okamura, Toshimitsu; Sander, Kerstin; Kikuchi, Tatsuya; Okada, Maki; Zhang, Ming-Rong; Robson, Mathew; Badar, Adam; Lythgoe, Mark; Koepp, Matthias; Arstad, Erik
Journal of Medicinal Chemistry, 2014 , vol. 57, # 3 p. 1023 - 1032
反应条件
1: 80 percent / n-BuLi / tetrahydrofuran; hexane / 17 h / Ambient temperature 2: 79 percent Spectr. / 4.5M H2SO4 / diethyl ether / Ambient temperature View Scheme
参考文献
Ogura, K.; Yamashita, M.; Suzuki, M.; Furukawa, S.; Tsuchinashi, G.
Bulletin of the Chemical Society of Japan, 1984 , vol. 57, # 6 p. 1637 - 1642
反应条件
1: 80 percent / n-BuLi / tetrahydrofuran; hexane / 17 h / Ambient temperature 2: 83 percent / 1.) H2SO4, 2.) K2CO3 / ethanol / Ambient temperature; 1.) 14h, 2.) 30min View Scheme
参考文献
Bulletin of the Chemical Society of Japan, , vol. 57, # 6 p. 1637 - 1642
反应条件
caesium carbonate in N,N-dimethyl-formamide
T=20°C; 144 h;
参考文献
Parker, Laurie L.; Gowans, Nicholas D.; Jones, Stephen W.; Robins, David J.
Tetrahedron, 2003 , vol. 59, # 51 p. 10165 - 10171
反应条件
2: NaBH4 / ethanol
3: pyridine, DMAP
4: 78 percent / LiBHEt3
5: 79 percent / PCC-alumina
6: 93 percent / H2 / Pd/C
View Scheme
参考文献
Takahashi, Takashi; Yamada, Haruo; Haino, Takeharu; Kido, Yoichi; Fukazawa, Yoshimasa
Tetrahedron Letters, 1992 , vol. 33, # 49 p. 7561 - 7564
反应条件
n-butyllithium in tetrahydrofuran; hexane
17 h; Ambient temperature;
参考文献
Ogura, K.; Yamashita, M.; Suzuki, M.; Furukawa, S.; Tsuchinashi, G.
Bulletin of the Chemical Society of Japan, 1984 , vol. 57, # 6 p. 1637 - 1642
反应条件
potassium carbonate in acetone
T=45°C; 24 h; Inert atmosphere;
参考文献
Dornan, Peter K.; Leung, Priscilla L.; Dong, Vy M.
Tetrahedron, 2011 , vol. 67, # 24 p. 4378 - 4384
