2,6-二溴-4-甲基苯酚合成路线 （共 81 条）
反应条件
1: 81 percent / DDQ / methanol / 1 h / Ambient temperature 2: 88 percent / NaBH4 / methanol View Scheme
参考文献
Sudalai, A.; Rao, G. S. Krishna
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1989 , vol. 28, # 1-11 p. 858 - 859
反应条件
in diethyl ether T=37°C; 24 h;
参考文献
Huddle, Penelope A.; Perold, Guido W.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 2617 - 2625
反应条件
sodium nitrite in acetic acid
参考文献
Hardcastle, Ian R.; Hunter, Ruth F.; Quayle, Peter; Edwards, Philip N.
Tetrahedron Letters, 1994 , vol. 35, # 22 p. 3805 - 3808
参考文献
Thiele; Eichwede
Justus Liebigs Annalen der Chemie, 1900 , vol. 311, p. 366 Anm.
参考文献
Zincke; Emmerich
Justus Liebigs Annalen der Chemie, 1905 , vol. 341, p. 311
参考文献
Thiele; Eichwede
Justus Liebigs Annalen der Chemie, 1900 , vol. 311, p. 366 Anm.
反应条件
1: sodium hydroxide / water; 1,2-dichloro-ethane / 5 h / 30 - 35 °C 2: copper(l) chloride / methanol; N,N-dimethyl-formamide / 8 h / 140 °C / |Autoclave View Scheme
参考文献
Sankaranarayanan, Ananthakrishnan; Chandalia
Organic Process Research and Development, 2006 , vol. 10, # 3 p. 487 - 492
反应条件
1: 4.6 percent / bromine, potassium bromide, pyridine / H2O; diethyl ether / 0.17 h / -5 °C 2: trifluoromethanesulfonic acid / CH2Cl2 / 0 °C 3: 54percent HI / H2O / 3 h / Heating 4: 84 percent Chromat. / bromine, triflic acid / 0.33 h View Scheme
参考文献
Fischer, Alfred; Henderson, George Narayanan
Canadian Journal of Chemistry, 1983 , vol. 61, p. 1045 - 1052
反应条件
aluminium trichloride T=130°C;
参考文献
Journal of the Chemical Society, , p. 525
反应条件
aluminium trichloride T=100°C;
参考文献
Journal of the Chemical Society, , p. 525
